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Table 1 Clinical data of severe sepsis subjects

From: Renin-angiotensin system activation correlates with microvascular dysfunction in a prospective cohort study of clinical sepsis

 

Mean

Range

Age (years)

56

31 to 85

Mean arterial pressure (mm Hg)

69

48 to 91

Heart rate (beats/min)

91

51 to 124

SpO2 (%)

97

90 to 100

Hemoglobin, (g/dL) during NIRS

11

8.6 to 22.4

Blood Lactate*, maximum value

3.7

0.7 to 10.3

Serum Creatinine, (mg/dL)

2

0.5 to 7.6

SOFA Score

10

1 to 19

 

n

%

   Total enrolled

30

100

   Male gender

17

57

   Severe organ failure†

14

47

   Vasoconstrictor use‡

21

70

   Mechanical Ventilation

21

70

   Survive, in-hospital

20

67

   Source of Infection

  

Pneumonia

15

50

Genitourinary

5

17

Abdominal

5

17

Endovascular‡‡

4

13

Multiple foci

1

3

  1. SpO2, arterial oxygen saturation by pulse oximetry; SOFA, sequential organ failure assessment. *n = 25 subjects. †Severe organ failure defined as SOFA ≥ 10. ‡ Vasoconstrictor use includes dopamine > 5 mcg/kg/min or any dose of norepinephrine or vasopressin. ‡‡Endovascular denotes bacteremia without detectable extravascular source of infection.