Figure 3From: Renin-angiotensin system activation correlates with microvascular dysfunction in a prospective cohort study of clinical sepsisMicrovascular responses to reactive hyperemia correlate inversely with organ dysfunction in severe sepsis. The microvascular response to reactive hyperemia was assessed by NIRS measures of thenar reoxygenation rates following induced forearm ischemia in 28 subjects. Correlation analysis showed a significant inverse relationship between microvascular reoxygenation rates and the degree of organ failure as assessed with the Sequential Organ Failure Assessment (SOFA) score (Pearson r = -0.50, P = 0.007).Back to article page