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Table 1 Study design and population characteristics:

From: Effect of different components of triple-H therapy on cerebral perfusion in patients with aneurysmal subarachnoid haemorrhage: a systematic review

Reference Study design
  Intervention type Prophylactic/Therapeutic Prospective Consecutive series Randomized Control group
Ekelund, 2002 [18] isovolemic hemodilution or hypervolemic hemodilution Therapeutic + unknown - -
Mori, 1995 [14] hypervolemic hemodilution Therapeutic + unknown - +
Yamakami, 1987 [21] hypervolemia Prophylactic + unknown - -
Lennihan, 2000 [13] hypervolemia Prophylactic + + + +
Tseng, 2003 [23] hypervolemia Therapeutic + unknown - -
Jost, 2005 [22] hypervolemia Therapeutic + - - -
Muizelaar, 1986 [25] hypertension Therapeutic unknown - - -
Touho, 1992 [20] hypertension Both unknown unknown - -
Darby, 1994 [24] hypertension Therapeutic - - - -
Origitano, 1990 [15] Triple-H Prophylactic + + - -
Muench, 2007 [19] Triple-H or hypertension or hypervolemic hemodilution Prophylactic + unknown - -
Reference Population Characteristics
  Nr. Int/noInt Mean age Men Clinical condition on admission: Type, median Int/no Int (range) Good Recovery or moderate Disability: Int/no Int Severe Disability or death: Int/no Int
Ekelund, 2002 [18] 8/0 42 13% H&H, 2 (1 to 3) 100% 0%
Mori, 1995 [14] 51/47 56 38% H&H, 2/2 (1 to 4) 82%/unknown 18%/unknown
Yamakami, 1987 [21] 35/0 51 31% H&H, ? (1 to 4) 86% 14%
Lennihan, 2000 [13] 41/41 48.5 41% H&H, 2/2 (1 to 4) 80%/76% 17%/20%
Tseng, 2003 [23] 6/0 50 unknown WFNS, ? (4 to 5) unknown unknown
Jost, 2005 [22] 6/0 49 50% unknown unknown unknown
Muizelaar, 1986 [25] 4/0 44 0% H&H, 4 (2 to 5) 100% 0%
Touho, 1992 [20] 20/0 55 55% H&H, 2 (2 to 4) 90% 10%
Darby, 1994 [24] 13/0 59 23% H&H, 2.5 (1 to 5) unknown unknown
Origitano, 1990 [15] 43/0 46 35% H&H, 2 (1 to 4) 84% 16%
Muench, 2007 [19] 10/0 53 20% H&H, ? (2 to 5) unknown unknown
  1. DCI, delayed cerebral ischemia; H&H, Hunt and Hess grading scale for subarachnoid hemorrhage [10]; Int, Intervention; WFNS, World Federation of Neurological Surgeons score [11]