Figure 1
From: Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication
Relation between cardiac index and arterio-venous difference in oxygen content in biguanide-intoxicated patients. Cardiac index (CI) and arterio-venous difference in oxygen content [C(a-v)O2] recorded during the first 4 days of admission from 11 biguanide-intoxicated patients. Each circle refers to individual data averaged on a daily basis. The arterio-venous difference in oxygen content was computed from either mixed (black circles) or central (white circles) venous oxygen saturation. Dotted lines refer to the lower and upper limits of normal systemic oxygen consumption (110 to 160 ml/min/m2). Circles that are located under the lower dotted line indicate an arterio-venous difference in oxygen content (oxygen extraction) lower than expected if systemic oxygen consumption is normal.