Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation

Table 2 Hemodynamic data

	NT	HT	HT+SEV	P value
Baseline
HR, beats/minute	107 ± 21	105 ± 14	96 ± 15	0.342
MAP, mm Hg	65 ± 13	70 ± 11	71 ± 13	0.314
ETCO₂, mm Hg	40 ± 5	36 ± 4	37 ± 5	0.180
CI, L/min/m²	7.4 ± 1.8	6.8 ± 1.3	7.4 ± 1.7	0.580
ROSC
HR, beats/minute	94 ± 18	99 ± 33	96 ± 21	0.988
MAP, mm Hg	55 ± 6	65 ± 21	60 ± 8	0.225
ETCO₂, mm Hg	39 ± 9	42 ± 4	39 ± 7	0.363
CI, L/min/m²	4.4 ± 0.5	4.5 ± 1.9	4.6 ± 1.0	0.982
Seven hours ROSC
HR, beats/minute	131 ± 17	140 ± 22	127 ± 20	0.821
MAP, mm Hg	58 ± 4	59 ± 12	61 ± 8	0.820
ETCO₂, mm Hg	37 ± 7	35 ± 4	35 ± 2	0.731
CI, L/min/m²	6.2 ± 0.4	5.5 ± 1.1	7.1 ± 1.2	0.071
24 hours ROSC
HR, beats/minute	154 ± 25	143 ± 19	124 ± 24	0.297
MAP, mm Hg	46 ± 6	57 ± 12	54 ± 4	0.249
ETCO₂, mm Hg	37 ± 4	41 ± 1	37 ± 2	0.180
CI, L/min/m²	5.6 ± 0.2	7.1 ± 1.6	8.7 ± 1.8	0.139

Hemodynamic data were determined at baseline, following return of spontaneous circulation (ROSC), and 7 and 24 hours after ROSC. HR indicates heart rate; MAP, mean arterial blood pressure; ETCO₂, end-tidal carbon dioxide, CI, cardiac index; NT, normothermia; HT, hypothermia; HT+SEV, hypothermia combined with sevoflurane. Data are mean ± SD.

ISSN: 1364-8535