Risk factors for multidrug resistant bacteria and optimization of empirical antibiotic therapy in postoperative peritonitis

Table 2 Characteristics and clinical findings at reoperation in the 100 patients with PP

Variable	Patients with MDR bacteria (n = 41)	Patients with other bacteria (n = 59)	P
APACHE II, mean ± SD	21 ± 7	21 ± 7	0.90
SOFA, mean ± SD	7 ± 4	7 ± 4	0.63
≥ 1 organ failures, n (%)	32 (78)	48 (81)	0.68
Vasopressor support, n (%)	26 (63)	41 (69)	0.38
Time to reoperation (days), mean ± SD	13 ± 16	10 ± 11	0.55
Mechanisms of PP
Anastomotic leakage, n (%)	14 (34)	20 (34)	0.98
Perforation, n (%)	9 (22)	21 (36)	0.14
Miscellaneous, n (%)	8 (20)	10 (17)	0.98
Unknown cause, n (%)	10 (24)	8 (14)	0.27
Source of PP
Lower intestinal tract, n (%)	16 (39)	32 (54)	0.67

APACHE, acute physiology and chronic health evaluation; MDR, multidrug resistant; PP, postoperative peritonitis; SD, standard deviation; SOFA, Sequential Organ Failure Assessment.

ISSN: 1364-8535