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Table 1 Demographic characteristics at initial surgery S0, and interval antibiotic therapy in the 100 patients with PP.

From: Risk factors for multidrug resistant bacteria and optimization of empirical antibiotic therapy in postoperative peritonitis

Variable

Patients with MDR bacteria (n = 41)

Patients with other bacteria (n = 59)

P

Age (year), mean ± SD

63 ± 17

60 ± 16

0.37

Gender, male, n (%)

24 (59)

32 (54)

0.83

Severity of underlying disease

   

   Fatal (within 5 years), n (%)

16 (39)

21 (36)

0.92

   Malignancy, n (%)

17 (41)

22 (37)

0.86

   Diabetes mellitus, n (%)

7 (17)

11 (19)

0.91

   Steroids or immunosuppressive therapy, n (%)

15 (37)

27 (46)

0.36

Initial surgery

   

   In emergency, n (%)

20 (49)

15 (25)

0.01

   Contaminated or infected wound class, n (%)

25 (61)

19 (32)

0.016

   Prior hospitalization (within 3 months prior S0), n (%)

24 (59)

29 (49)

0.24

   Prior antibiotic therapy (within 3 months, prior S0), n (%)

18 (44)

13 (22)

0.02

Interval antibiotics, n (%)

33 (80)

35 (59)

0.026

Broad-spectrum interval antibiotics, n (%)

25 (61)

11 (19)

0.0001

  1. MDR, multidrug resistant; PP, postoperative peritonitis; SD, standard deviation; S0, initial abdominal surgery.