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Figure 5 | Critical Care

Figure 5

From: Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury

Figure 5

Changes in brain glutamate (grey box plots) and calculated brain lactate-to-glutamate (white box plots) ratio determined by microdialysis reflecting influence of brain glucose on downstream cerebral metabolism in pre-defined brain glucose clusters, ranging from less than 1 mM to more than 9 mM in 1 mM buckets. At brain glucose levels exceeding 5 mM brain glutamate was significantly increased. In parallel lactate-to-glutamate was significantly decreased. Changes across the pre-defined brain glucose clusters compared with low brain glucose levels were significant (*P < 0.001; analysis of variance on ranks, post hoc Dunn's test).

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