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Figure 3 | Critical Care

Figure 3

From: Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury

Figure 3

Changes in brain glutamate (grey box plots) and calculated lactate-to-glutamate (white box plots) ratio determined by microdialysis reflecting influence of blood glucose on downstream cerebral metabolism in pre-defined arterial blood glucose clusters, ranging from less than 5 mM to more than 9 mM in 1 mM buckets. At arterial blood glucose levels exceeding 6 mM brain glutamate was significantly increased. In parallel, calculated lactate-to-glutamate was significantly decreased. Alterations across the pre-defined blood glucose clusters compared with low arterial blood glucose levels were significant (*P < 0.001; analysis of variance on ranks, post hoc Dunn's test).

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Critical Care

ISSN: 1364-8535