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Table 3 Simple and multiple linear regression analysis with neutrophil gelatinase-associated lipocalin as dependent variable

From: Serum neutrophil gelatinase-associated lipocalin at inception of renal replacement therapy predicts survival in critically ill patients with acute kidney injury

  Simple model Multiple model
Variable B Pvalue β Pvalue
Sepsis (yes/no) 0.37 <0.0001 0.33 < 0.001
RIFLE category failure* 0.23 0.018 0.04 0.693
ln SOFA - total 0.16 0.098 0.03 0.738
   ln SOFA - respiratory variable 0.17 0.075 0.13 0.140
   ln SOFA - renal variable 0.22 0.020 0.23 0.007
ln CRP 0.40 <0.0001 0.21 0.031
ln cystatin C 0.34 <0.0001 0.26 0.005
  1. Multiple linear regression analysis using neutrophil gelatinase-associated lipocalin as the dependent variable. Variables found to be statistical significant at a P value less than 0.1 in the simple model were included into the multiple linear regression analysis using stepwise backward elimination. Variables that were not normally distributed were log transformed. (β denotes standardized regression coefficient); A two-sided P value of less than 0.05 was considered statistically significant in the multiple model. * β for categorical variables is only displayed in case of multivariate significance.
  2. CRP = C reactive protein; RIFLE = a newly developed international consensus classification for acute kidney injury, that defines three grades of severity - risk (class R), injury (class I) and failure (class F); SOFA = Sequential Organ Failure Assessment score.