Table 3 Adjusted estimates for control vs active on PRBC transfusion requirements and mortality outcomes
PRBC transfusion (unit/patient/day) | ICU Mortality | Hospital Mortality | ||||
|---|---|---|---|---|---|---|
B Estimate (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
Control vs Active | 0.063 (0.010, 0.116) | 0.02 | 0.34 (0.19, 0.60) | < 0.001 | 0.36 (0.20, 0.63) | < 0.001 |
Age (years) | -0.003 (-0.005, -0.002) | < 0.001 | 0.99 (0.97, 1.01) | 0.268 | 0.99 (0.98, 1.01) | 0.608 |
Male vs Female | -0.035 (-0.085, 0.014) | 0.158 | 1.1 (0.61, 1.9) | 0.782 | 1.2 (0.7, 2.1) | 0.502 |
APACHE II score | 0.003 (-0.001, 0.007) | 0.067 | 1.01 (0.97, 1.05) | 0.589 | 1.004 (0.97, 1.04) | 0.82 |
Hb before transfusion (g/dL) | 0.050 (0.041, 0.059) | < 0.001 | 0.95 (0.86,1.05) | 0.337 | 0.98 (0.89, 1.08) | 0.647 |
Hb on admission (g/dL) | -0.001 (-0.011, 0.009) | 0.842 | 0.92 (0.82,1.03) | 0.157 | 0.95 (0.85, 1.06) | 0.331 |
ICU LOS (days) | -0.006 (-0.009, -0.002) | 0.001 | 0.99 (0.95, 1.03) | 0.627 | 0.99 (0.95, 1.03) | 0.616 |
RRT (Duration, hours) | 0.0003 (-0.0001, 0.001) | 0.197 | 1.004 (0.99, 1.01) | 0.176 | 1.001 (0.99, 1.007) | 0.646 |