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Figure 4 | Critical Care

Figure 4

From: Association between regulatory T cell activity and sepsis and outcome of severely burned patients: a prospective, observational study

Figure 4

SYBR green real-time RT-PCR analysis for mRNA expression of IL-10 and TGF-β1 in Tregs. Enhanced gene expressions of (a) IL-10 and (b) TGF-β1 in regulatory T cells (Tregs) from burned patients were detected on postburn days (PBD) 1 to 21 in comparison with normal controls, and there were obvious differences among patients with different extent of burn injury. mRNA expressions of (c) IL-10 and (d) TGF-β1 in Tregs were significantly higher in septic patients than those without sepsis on PBD 3 to 21. Among septic patients, (e) IL-10 and (f) TGF-β1 mRNA expressions in the survival group were markedly lower than those with fatal outcome on PBD 3 to 21. *P < 0.01, **P < 0.01, Group I vs. normal group or sepsis group vs. non-sepsis group, or non-survivors group vs. survivors group; #P < 0.01, ##P < 0.01, Group II vs. Group I; &P < 0.05, &&P < 0.01, Group III vs. Group II.

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Critical Care

ISSN: 1364-8535