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Figure 3 | Critical Care

Figure 3

From: Association between regulatory T cell activity and sepsis and outcome of severely burned patients: a prospective, observational study

Figure 3

ELISA analysis of IL-10 and TGF-β1 levels in Tregs supernatants. Elevated protein expressions of IL-10 and TGF-β1 in regulatory T cells (Tregs) from burned patients were detected on postburn days (PBD) 1 to 21 in comparison to normal controls, and there were obvious differences among patients with different extent of burn injury ((a and b) a mean of all days). Protein levels of (c) IL-10 and (d) TGF-β1 in Tregs were significantly higher in septic patients than those without sepsis on PBD 3 to 21. Among septic patients, (e) IL-10 and (f) TGF-β1 levels in the survivors were obviously lower than those with non-survivors on PBD 3 to 21. **P < 0.01, Group I vs. normal group, or sepsis group vs. non-sepsis group or non-survivors group vs. survivors group; ##P < 0.01, Group II vs. Group I; &P < 0.05, &&P < 0.01, Group III vs. Group II.

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Critical Care

ISSN: 1364-8535