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Figure 2 | Critical Care

Figure 2

From: Association between regulatory T cell activity and sepsis and outcome of severely burned patients: a prospective, observational study

Figure 2

Flow cytometric analysis of phenotypes of Tregs. Increased expressions of CTLA-4 and FOXP3 on the surface of regulatory T cells (Tregs) from burned patients were found on postburn days (PBD) 1 to 21 compared with normal controls, and there were obvious differences among patients with various burn sizes ((a and b) a mean of all days). The expressions of CTLA-4 and FOXP3 were significantly higher in patients with serious burns during the whole observational period, and (c and d) they were much higher in septic patients than those without sepsis on PBD 3 to 21. (e and f) Among septic patients, the expressions of CTLA-4 and FOXP3 in the survival group were obviously lower than those in non-survival group on PBD 3 to 21. * P < 0.05, ** P < 0.01, Group I vs. normal group or sepsis group vs. non-sepsis group or non-survivors vs. survivors; #P < 0.05, ## P < 0.01, Group II vs. Group I; &P < 0.05, Group III vs. Group II.

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Critical Care

ISSN: 1364-8535