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Table 3 Gas exchange and hemodynamic parameters before, during and after extracorporeal support

From: A new miniaturized system for extracorporeal membrane oxygenation in adult respiratory failure

 

Pre ECMO

2 Hours

Day 1

Day 2

End of ECMO, Survivors

End of ECMO,

Non-Survivors

Day 1 after ECMO

PaO 2 /FiO 2 (mm Hg)

64

(48 to 86)

120 **

(84 to 171)

125 **

(108 to 160)

148 **

(108 to 191)

218 **

(181 to 290)

174 **

(136 to 193)

194 **

(144 to 245)

PaCO 2 (mm Hg)

63

(50 to 80)

33 **

(29 to 39)

36 **

(31 to 41)

37 **

(32 to 40)

40 **

(35 to 46)

35 **

(27 to 42)

44 **

(36 to 49)

pH

7.20

(7.13 to 7.30)

7.42 **

(7.34 to 7.49)

7.43 **

(7.37 to 7.49)

7.44 **

(7.38 to 7.50)

7.43 **

(7.39 to 7.45)

7.31 *

(7.21 to 7.41)

7.41 **

(7.32 to 7.47)

MAP (mm Hg)

67

(59 to 76)

77 **

(69 to 86)

72 *

(66 to 79)

76 **

(70 to 87)

80 *

(71 to 90)

65

(55 to 72)

80 *

(70 to 86)

Norepinephrine (μg/kg/min)

0.35

(0.15 to 0.84)

0.28 **

(0.12 to 0.55)

0.15 **

(0.04 to 0.29)

0.10 **

(0.04 to 0.24)

0.00 **

(0.00 to 0.05)

0.27

(0.06 to 0.67)

0.00 **

(0.00 to 0.07)

O 2 transfer ECMO

(mL/min)

 

155

(116 to 182)

157

(128 to 178)

160

(129 to 195)

80 **

(74 to 93)

111

(99 to 160)

 

CO 2 transfer ECMO

(mL/min)

 

210

(164 to 251)

193 *

(164 to 218)

195

(158 to 232)

116 **

(96 to 150)

170

(136 to 225)

 

ECMO flow (L/min)

 

2.7

(2.5 to 3.0)

2.8

(2.5 to 3.1)

2.9 *

(2.5 to 3.2)

1.6 **

(1.5 to 1.8)

2.0 *

(1.8 to 3.0)

 
  1. The measurement at the end of extracorporeal support is separated in survivors and non-survivors (to discharge).
  2. Data are presented as median (interquartile range). * P < 0.05, ** P < 0.001 to first measurement. (ECMO = extracorporeal membrane oxygenation, MAP = mean arterial pressure)