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Figure 4 | Critical Care

Figure 4

From: Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model

Figure 4

Changes in HMGB1. The high-mobility group box 1 (HMGB1) level increased at 8 h after the treatment of lipopolysaccharide (LPS) treatment in the control group (n = 7). The levels were lower in antithrombin (AT, n = 7), recombinant human soluble thrombomodulin (TM, n = 7) and AT/TM groups (n = 7) and were approximately one-third of that in the control group; however, the differences were not rstatistically significant (P < 0.1, each). N = normal; C = control.

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