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Figure 2 | Critical Care

Figure 2

From: Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model

Figure 2

Changes in coagulation markers. The platelet count had decreased significantly at eight hour after lipopolysaccharide (LPS) injection in the control group (n = 7). This depletion was slightly suppressed in both the antithrombin (AT) and thrombomodulin (TM) groups (n = 7 each); however, the differences were not statistically significant. Meanwhile, the platelet count in the AT/TM group was significantly higher in the AT/TM group (n = 7). Similarly, the fibrinogen level was significantly depressed at eight hours after LPS injection in the control group (n = 7) and this depletion was suppressed in the AT and TM groups; however, the differences were not statistically significant. The level was best maintained in the AT/TM group (P < 0.01, n = 7). N = normal; C = control.

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Critical Care

ISSN: 1364-8535