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Table 1 Clinical and laboratory characteristics of the patients

From: Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza

  Hospitalized, critical illness(n = 10) Hospitalized, non critical illness (n = 10)
Pathological antecedents   
Esquizophrenia 1/10 -
COPD 1/10 -
Diabetes 2/10 -
Asthma - 2/10
COPD+HIV - 1/10
Chronic disease conective tissue - 1/10
Dyslipemia 1/10 -
Cardiopathy 1/10 -
Hypertension 1/10 -
Obesity (BMI>30) 5/10 3/10
Descriptives   
Age (yrs) 41.8 (9.9) 31.3 (10.9)
Sex (M/F) 6/4 6/4
Days at hospital 29.5 (29.2) 6.5 (2.8)
Days at ICU 26.6 (30.8) 0 (0)
Severity scores   
SOFA score 5.6 (2.9) -
APACHEII score 12.8 (4.2) -
Respiratory condition   
Mechanical Ventilation 9/10 0/10
O2 saturation (%) 83.3 (7.3) 93.0 (5.1)
PaO2 (mmHg) 54.1 (11.6) 76.5 (24.3)
PaO2:FiO2 94.0 (89.9) 252.5 (20.6)
Opacity in initial chest X-Ray   
0/4 quadrants 0/10 4/10
1/4 quadrants 2/10 3/10
2/4 quadrants 3/10 3/10
3/4 quadrants 0/10 0/10
4/4 quadrants 5/10 0/10
Biochemistry   
LDH (IU/liter) 1634 (1226.0) 475.1 (356.7)
CPK (IU/liter) 588.5 (606.1) 108.5 (132.1)
GOT (U/liter) 126.9 (73.5) 35.6 (14.5)
GPT (U/liter) 130.7 (97.6) 35.7 (18.9)
Glucose (mg/dl) 202.7 (97.1) 113.1 (29.1)
CRP (mg/l) 85.4 (76.3) 61.1 (105.1)
Treatment received at the time of sample collection   
Oseltamivir 10/10 (75-150 mg/12 hs) 10/10 (75 mg/12 hs)
Cephalosporines 6/10 2/10
Macrolides 3/10 1/10
Quinolones 5/10 7/10
Steroids 4/10 (parenteral) 2/10 (inhaled)
Noradrenaline 5/10 0/10
Renal replacement therapy 2/10 0/10
  1. COPD = Chronic Obstructive Pulmonary Disease; HIV = Human Immunodeficiency Virus; BMI = Body Mass Index; ICU = Intensive Care Unit; SOFA = Sepsis-related Organ Failure Assessment score; APACHE II = Acute Physiology and Chronic Health Evaluation II; PaO2 = pressure of oxygen in arterial blood; FiO2 = fraction of inspired oxygen; LDH = Lactate dehydrogenase; CPK = creatine phosphokinase; GOT = Glutamyl oxaloacetic transaminase; GPT = Glutamyl pyruvic transaminase; CRP = C Reactive Protein; IU = International Units; U = Units.