Table 1 Clinical and laboratory characteristics of the patients
From: Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza
Hospitalized, critical illness(n = 10) | Hospitalized, non critical illness (n = 10) | |
|---|---|---|
Pathological antecedents | ||
Esquizophrenia | 1/10 | - |
COPD | 1/10 | - |
Diabetes | 2/10 | - |
Asthma | - | 2/10 |
COPD+HIV | - | 1/10 |
Chronic disease conective tissue | - | 1/10 |
Dyslipemia | 1/10 | - |
Cardiopathy | 1/10 | - |
Hypertension | 1/10 | - |
Obesity (BMI>30) | 5/10 | 3/10 |
Descriptives | ||
Age (yrs) | 41.8 (9.9) | 31.3 (10.9) |
Sex (M/F) | 6/4 | 6/4 |
Days at hospital | 29.5 (29.2) | 6.5 (2.8) |
Days at ICU | 26.6 (30.8) | 0 (0) |
Severity scores | ||
SOFA score | 5.6 (2.9) | - |
APACHEII score | 12.8 (4.2) | - |
Respiratory condition | ||
Mechanical Ventilation | 9/10 | 0/10 |
O2 saturation (%) | 83.3 (7.3) | 93.0 (5.1) |
PaO2 (mmHg) | 54.1 (11.6) | 76.5 (24.3) |
PaO2:FiO2 | 94.0 (89.9) | 252.5 (20.6) |
Opacity in initial chest X-Ray | ||
0/4 quadrants | 0/10 | 4/10 |
1/4 quadrants | 2/10 | 3/10 |
2/4 quadrants | 3/10 | 3/10 |
3/4 quadrants | 0/10 | 0/10 |
4/4 quadrants | 5/10 | 0/10 |
Biochemistry | ||
LDH (IU/liter) | 1634 (1226.0) | 475.1 (356.7) |
CPK (IU/liter) | 588.5 (606.1) | 108.5 (132.1) |
GOT (U/liter) | 126.9 (73.5) | 35.6 (14.5) |
GPT (U/liter) | 130.7 (97.6) | 35.7 (18.9) |
Glucose (mg/dl) | 202.7 (97.1) | 113.1 (29.1) |
CRP (mg/l) | 85.4 (76.3) | 61.1 (105.1) |
Treatment received at the time of sample collection | ||
Oseltamivir | 10/10 (75-150 mg/12 hs) | 10/10 (75 mg/12 hs) |
Cephalosporines | 6/10 | 2/10 |
Macrolides | 3/10 | 1/10 |
Quinolones | 5/10 | 7/10 |
Steroids | 4/10 (parenteral) | 2/10 (inhaled) |
Noradrenaline | 5/10 | 0/10 |
Renal replacement therapy | 2/10 | 0/10 |