Clinical review: Scoring systems in the critically ill

Table 2 Comparison of three organ dysfunction scores

Characteristics	LODS[29]	MODS[30]	SOFA[31]
Year of publication	1996	1995	1996
Selection of variables and their weights	Multiple logistic regression	Literature review and logistic regression	Panel of experts
Variables used to assess organ dysfunction
Neurologic	Glasgow Coma Scale	Glasgow Coma Scale	Glasgow Coma Scale
Cardiovascular	Heart rate, systolic blood pressure	Pressure-adjusted heart rate	Mean arterial blood pressure, vasopressor use
Renal	Serum urea or urea nitrogen, creatinine, urine output	Serum creatinine	Serum creatinine, urine output
Respiratory	PaO₂/FiO₂ ratio, mechanical ventilation	PaO₂/FiO₂ Ratio	PaO₂/FiO₂ ratio, mechanical ventilation
Hematologic	White blood cell count, platelet count	Platelet count	Platelet count
Hepatic	Serum bilirubin, prothrombin time	Serum bilirubin	Serum bilirubin

LODS, Logistic Organ Dysfunction Score; MODS, Multiple Organ Dysfunction Score; SOFA, Sequential Organ Dysfunction Score.

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