Table 4 Comparison of baseline markers of coagulation and circuit life between patients with SOFA score of 10 or less (median) and those with SOFA score of more than 10

Baseline (arterial)

antithrombin (%)

58 (34-79)

52 (36-86)

0.24

anti-Xa (IU/ml)

0.06 (0.00-0.15)

0.11 (0.00-0.55)

0.94

PTT (sec)

11.4 (11.0-11.5)

12.0 (11.4-24.2)

0.004

aPTT (sec)

24.3 (20.3-35.1)

36.2 (27.5-95.3)

0.02

Platelets (10⁹/L)

143 (96-221)

179 139-267)

0.54

ETP_Tlag (sec)

19.7 (18.4-22.1)

23.0 (18.6-31.0)

0.24

ETP_Tmax (sec)

54.8 (51.6-55.7)

48.5 (39.6-54.8)

0.37

ETP_Cmax

139 (113-153)

97 (61-119)

0.05

ETP_AUC (mA)

359 (246-437)

187 (118-279)

0.08

F1+2 (pmol/L)

216 (125-288)

314 (165-689)

0.81

TAT (μg/L)

7.4 (5.2-9.0)

20.7 (15.1-29.0)

0.008

D-dimers (μg/ml)

9 (1.5-29.8)

14 (4.3-43.8)

0.47

circuit life (h)

32 (25-39)

12 (4-24)

0.002

during CVVH and nadroparin infusion (arterial)

during CVVH (postfilter)

anti-Xa (IU/ml)

0.28 (0.20-0.45)

0.16 (0.10-0.38)

0.008

0.53 (0.35-0.71)

0.32 (0.24-0.54)

0.003

PTT (sec)

11.3 (11.0-11.8)

11.4 (10.8-14.6)

0.18

10.7 (10.2-11.2)

10.7 (10.3-12.4)

0.10

aPTT (sec)

26 (21.9-32.2)

28.6 (27.1-36.6)

0.001

25.9 (21.7-30.8)

28.7 (25-5.32.5)

0.006

Platelets (10⁹/L)

140 (116-196)

160 (119-251)

0.65

176 (138-217)

193 (154-281))

0.85

ETP_Tlag (sec)

20.3 (16.7-22.3)

18.8 (15.8-23.8)

0.61

17.1 (13.0-21.3)

18.3 (16.1-24.2)

0.06

ETP_Tmax (sec)

45.8 (40.4-54.7)

50.8 (42.8-60.2)

0.13

40.1 (34.7-43.7)

45.8 (36.6-52.6)

0.04

ETP_cmax (mA/min)

119 (89-146)

109 (89-132)

0.13

145 (111-183)

123 (97-134)

0.003

ETP_AUC (mA)

267 (167-350)

244 (161-294)

0.24

218 (87-307)

169 (76-268)

0.30

F1+2 (pmol/L)

202 (134-330)

301 (219-500)

0.88

307 (157-429)

471 (314-793)

0.78

TAT (μg/L)

5.3 (4.8-7.4)

16.2 (7.1-36.8)

< 0.001

7.9 (6.4-13.4)

27 (13.3-58.4)

< 0.001

D-dimers (μg/ml)

7.6 (2.1-21.2)

19.7 (4.4-37.6)

0.004

10.7 (3.1-34.8)

28.6 (7.3-51.4)

0.002