Table 2 Comparison of markers of coagulation during CVVH in arterial and postfilter blood between randomized groups
during CVVH and nadroparin infusion (arterial) | during CVVH (postfilter) | |||||
|---|---|---|---|---|---|---|
| Â | Group 1 4 to 2 L/h | Group 2 2 to 4 L/h | P value | Group 1 4 to 2 L/h | Group 2 2 to 4 L/h | P value |
anti-Xa (IU/ml) | 0.19 (0.12-0.37) | 0.31 (0.23-0.52) | 0.02 | 0.34 (0.25-0.44) | 0.51 (0.41-0.76) | 0.005 |
PTT (sec) | 11.1 (10.8-12.6) | 11.5 (11.1-12.8) | 0.30 | 10.7 (10.2-12.0) | 11.1 (10.4-11.8) | 0.80 |
aPTT (sec) | 28.0 (25.4-33.3) | 29.3 (22.1-40.5) | 0.95 | 27.0 (24.5-30.7) | 28.3 (22.2-35.2) | 0.80 |
platelets (109/l) | 164 (131-242) | 129 (114-210) | 0.05 | 200 (161-276) | 172 (140-274) | 0.23 |
ETPTlag (sec) | 18.5 (16.7-23.6) | 20.9 (15.1-23.2) | 0.84 | 18.1 (15.5-23.4) | 17.8 (12.9-22.3) | 0.30 |
ETPTmax (sec) | 47.2 (41.5-56.6) | 45.8 (40.9-55.0) | 0.93 | 43.9 (34.8-52.0) | 40.1 (35.0-43.8) | 0.19 |
ETPCmax (mA/min) | 113 (96-141) | 115 (83-134) | 0.25 | 127 (100-149) | 143 (99-166) | 0.21 |
ETPAUC (mA) | 280 (175-338) | 209 (109-209) | 0.03 | 212 (99-309) | 189 (38-289) | 0.45 |
F1+2 (pmol/L) | 298 (198-482) | 228 (159-332) | 0.06 | 456 (306-787) | 320 (188-455) | 0.008 |
TAT (μg/L) | 9.3 (6.7-23) | 5.5 (4.8-9.6) | 0.001 | 20 (9.2-53.8) | 8.3 (6.2-17.6) | 0.001 |
D-dimers (μg/ml) | 11.1 (7.8-29.5) | 3.8 (2.0-24.8) | 0.03 | 17.8 (11.0-43.2) | 5.7 (3.1-41.8) | 0.14 |