Clinical relevance of the interleukin 10 promoter polymorphisms in Chinese Han patients with major trauma: genetic association studies

Table 3 Distribution of the IL-10 promoter polymorphisms among trauma patients

Loci	Patients	n	MA (%)	Genotypes, n (%)			HWE
				wild	heterozygous	variant
A-1082G	All	308	15.4	224 (72.7)	73 (23.7)	11 (3.6)	0.11
	Sepsis	147	12.2	115 (78.2)	28 (19.1)	4 (2.7)
	Non-sepsis	161	18.3^a	109 (67.7)^b	45 (28)	7 (4.3)
T-819C	All	308	29.2	157 (51.0)	122 (39.6)	29 (9.4)	0.46
	Sepsis	147	29.3	73 (49.7)	62 (42.2)	12 (8.2)
	Non-sepsis	161	29.2	84 (52.2)	60 (37.3)	17 (10.6)
A-592C	All	307	34.0	141 (45.9)	123 (40.1)	43 (14.0)	0.07
	Sepsis	147	34.4	65 (44.2)	63 (42.9)	19 (12.9)
	Non-sepsis	160	33.8	76 (47.5)	60 (37.5)	24 (15.0)

Sepsis vs. non-sepsis: ^aP = 0.037, ^bP = 0.038. HWE = Hardy-Weinberg equilibrium; MA = minor allele.

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