Table 4 Laboratory parameters
From: Effect of fluid resuscitation on mortality and organ function in experimental sepsis models
Variable | Group | N | Baseline | End | Interactions | P |
|---|---|---|---|---|---|---|
Creatinine kinase - MB (U/L) |  |  |  |  | Time × volume effect: | 0.006 |
|  | Control 10 ml/kg | 8 | 0.9 ± 0.1 | 1.0 ± 0.2 |  |  |
|  | Control 20 ml/kg | 8 | 0.9 ± 0.1 | 1.2 ± 0.2 | ANOVArm high-volume: | 0.001 |
|  | Endotoxin 10 ml/kg | 8 | 1.0 ± 0.2 | 1.0 ± 0.2 |  |  |
|  | Endotoxin 20 ml/kg | 7 | 1.0 ± 0.2 | 1.1 ± 0.3 |  |  |
|  | Peritonitis 10 ml/kg | 8 | 1.1 ± 0.2 | 1.1 ± 0.3 |  |  |
|  | Peritonitis 20 ml/kg | 8 | 0.8 ± 0.3 | 1.3 ± 0.2 |  |  |
Creatinine (μmol/L) |  |  |  |  | Time × model effect: Time × volume effect: | 0.014 0.029 |
|  | Control 10 ml/kg | 8 | 87 ± 18 | 78 ± 17 | ANOVArm Control: | 0.007 |
|  | Control 20 ml/kg | 8 | 99 ± 13 | 74 ± 24 | ANOVArm high-volume: | 0.04 |
|  | Endotoxin 10 ml/kg | 8 | 86 ± 21 | 79 ± 16 |  |  |
|  | Endotoxin 20 ml/kg | 7 | 85 ± 15 | 74 ± 10 |  |  |
|  | Peritonitis 10 ml/kg | 8 | 81 ± 10 | 114 ± 31 |  |  |
|  | Peritonitis 20 ml/kg | 8 | 82 ± 17 | 76 ± 36 |  |  |
ALAT (U/L) |  |  |  |  | Time × volume effect: | 0.001 |
|  | Control 10 ml/kg | 8 | 18.1 ± 4.3 | 14.8 ± 4.5 |  |  |
|  | Control 20 ml/kg | 8 | 20.5 ± 10.5 | 11.3 ± 10.6 | ANOVArm high-volume: | 0.001 |
|  | Endotoxin 10 ml/kg | 8 | 17 ± 5.2 | 15.1 ± 4.3 |  |  |
|  | Endotoxin 20 ml/kg | 7 | 19 ± 5.7 | 11.4 ± 2.4 |  |  |
|  | Peritonitis 10 ml/kg | 8 | 16.9 ± 6.4 | 16.7 ± 11.2 |  |  |
|  | Peritonitis 20 ml/kg | 8 | 19.5 ± 9.2 | 11.3 ± 5 |  |  |
ASAT (U/L) | Â | Â | Â | Â | Â | Â |
|  | Control 10 ml/kg | 8 | 84 ± 31 | 60 ± 27 |  |  |
|  | Control 20 ml/kg | 8 | 114 ± 57 | 76 ± 23 |  |  |
|  | Endotoxin 10 ml/kg | 8 | 96 ± 23 | 86 ± 44 |  |  |
|  | Endotoxin 20 ml/kg | 7 | 136 ± 84 | 117 ± 23 |  |  |
|  | Peritonitis 10 ml/kg | 8 | 104 ± 43 | 129 ± 88 |  |  |
|  | Peritonitis 20 ml/kg | 8 | 101 ± 50 | 100 ± 55 |  |  |