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Table 2 Risk factors of hypotension during connection of CRRT in children

From: Complications of continuous renal replacement therapy in critically ill children: a prospective observational evaluation study

 

Hypotension

No hypotension

P

 

Mean

SD

Mean

SD

 

Age (months)

53.4

67.5

50.0

61.4

0.694

Weight (kg)

18.1

19.8

16.9

17.3

0.910

PRISM score

16.8

15.5

21.6

25.8

0.650

PIM score

10.1

13.4

10.9

16.8

0.874

PELOD score

25.7

30.2

20.7

22.7

0.294

Number of failed organs

3.2

1.2

2.8

1.1

0.139

Lactic acid (mmol/L)

3.2

3.3

3.0

3.8

0.357

Arterial pH

7.32

0.12

7.31

0.10

0.341

MAP (mmHg)

58.2

14.8

62.9

20.2

0.124

Dose of adrenaline (μg/kg/min)

0.4

0.5

0.57

1.3

0.734

Dose of dopamine (μg/kg/min)

9.1

6.6

9.0

6.6

0.932

Initial creatinine (mg/dL)

1.4

1.1

1.5

1.3

0.491

Initial urea (mg/dL)

79.2

61.4

86.2

59.6

0.236

ALT (UI/L)

523.5

1261.7

71.0

112.5

0.212

Billirubine (mg/dL)

1.8

1.6

1.8

2.4

0.667

Extracorporeal circuit volume/weight of patient (ml/kg)

8.6

4.6

8.8

5.3

0.982

 

Hypotension

Number %

Hypotension

Number %

 

Age

<12 m

>12 m

 
 

24

31.6

29

30.2

0.847

Sex

Male

Female

 
 

34

33

19

27.5

0.446

Weight

<10 kg

>10 kg

 
 

27

30

35

31.7

0.809

Diagnoses

Cardiopathies

Rest of diagnoses

 
 

31

32.6

22

28.6

0.566

Mechanical ventilation

Yes

No

 
 

48

33.1

5

18.5

0.132

Vasoactive drugs

Yes

No

 
 

42

30.9

11

30.6

0.970

Initial MAP

<55 mmHg

>55 mmHg

 
 

24

38.1

25

27.5

0.164

Dose of adrenaline

> 0.6 μg/kg/min

> 0.6 μg/kg/min

 
 

12

35.3

32

29.4

0.513

Filter surface

<0.3 m 2

>0.3 m 2

 
 

21

33.3

32

24.4

0.586

Extracorporeal circuit volume/weight of patient

> 5 ml/kg

< 5 ml/kg

 
 

36

32.1

10

22.2

0.217

Mortalilty

Yes

No

 
 

24

38.7

29

26.4

0.095

  1. ALT = alanine transferase; CRRT = continuous renal replacement therapy; MAP = mean arterial pressure; PELOD = pediatric logistic organ dysfunction; PIM = pediatric index of mortality; PRIMS = pediatric risk of mortality; SD = standard deviation.