Effect of cardiopulmonary bypass on activated partial thromboplastin time waveform analysis, serum procalcitonin and C-reactive protein concentrations

Table 4 Non septic SIRS vs. septic patients' characteristics

Data	Non septic SIRS (n = 11)	Sepsis (n = 5)	P value
Male/female	8/3	5/0	0.55
Age (years)	69 ± 10	61 ± 24	0.37
ASA physical status (III/IV)	7/4	2/3	0.72
Length of stay in the ICU (days)	5 (3-6)	14 (8-18)	0.26
SAPS II	34 (27-42)	23 (19-50)	0.76
EuroSCORE	9 ± 4	8 ± 1	0.67
LVEF <50%	3 (27%)	2 (40%)	0.95
*Baseline biologic measurements*
- WBC (G/L)	7.6 ± 2.4	6.9 ± 1.0	0.59
- CRP (mg/L)	6.4 (2.4-11.1)	10.9 (1.7-18.3)	0.96
- PCT (ng/L)	0.09 (0.08-0.18)	0.09 (0.07-0.20)	1
- BPW (%T/s)	0.02 ± 0.02	0.04 ± 0.03	0.27
*Surgical procedure (n)*
- Valvular surgery	7 (63%)	3 (60%)
- Combined surgery	2 (18%)	1 (20%)
- Ascending aorta surgery	2 (18%)	1 (20%)
- CABG	0	0
CPB duration (min)	118 (90-120)	139 (103-208)	0.31
Aortic cross clamping time (min)	84 ± 27	99 ± 39	0.39
*Post operative complications (n)*
- Reoperation	1 (9%)	3 (60%)	0.12
- Hemorrhage	2 (18%)	3 (60%)	0.27
- Tamponade	0	2 (40%)	0.15
- Inotropic support	3 (27%)	2 (40%)	0.95
- Myocardial infarction	0	1 (20%)	0.68
- AKI requiring RRT	1 (9%)	2 (40%)	0.43
Death (n)	2 (18%)	2 (40%)	0.75

Data are expressed as mean ± standard deviation, median (interquartile range), or number (percentage).
AKI = acute kidney injury; ASA = American Society of Anesthesiology; BPW = biphasic waveform; CABG = coronary artery bypass grafting; CPB = cardiopulmonary bypass; CRP = C-reactive protein; EuroSCORE = European system for cardiac operative risk evaluation; ICU = intensive care unit; LVEF = left ventricular ejection fraction; PCT = procalcitonin; RRT = renal replacement therapy; SAPS II = simplified acute physiology score; SIRS = systemic inflammatory response syndrome.

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