Table 3 Parameters at initiation of RRT and ICU outcomeay

Serum creatinine (μmol/L)

≤ 200

456 (24.7%)

255 (55.9%)

(≤ 500 vs >500)

>200-500

1064 (57.6%)

609 (57.2%)

<0.0001

>500

278 (15.1%)

102 (36.7%)

2.27 (1.75-2.96)

≤ 309

953 (51.6%)

564 (59.2%)

<0.0001

>309 (50 data missing)

848 (45.9%)

404 (47.6%)

1.59 (1.32-1.92)

Serum pH

<7.2

397 (21.5%)

294 (74.1%)

(<7.2 vs

7.2-7.35

675 (36.5%)

385 (57.0%)

≥ 7.2) <0.0001

>7.35 (28 data missing)

747 (40.4%)

299 (40.0%)

0.32 (0.25-0.42)

Serum K ⁺ (mmol/L)

≤ 6

1634 (88.5%)

877 (53.7%)

>6 (28 data missing)

185 (10.0%)

101 (54.6%)

0.82

0.96 (0.71-1.31)

Urine output

<400 ml/24 hours

994 (53.8%)

595 (59.9%)

≥ 400 ml/24 hours

853 (46.2%)

404 (47.4%)

<0.0001

1.66 (1.38-1.99)

Serum HCO ₃ (mmol/L)

<10

50 (2.7%)

37 (74%)

(<15 vs

10-14.9

146 (7.9%)

103 (70.5%)

≥ 15)

≥ 15 (577 data missing)

1074 (58.1%)

565 (52.6%)

<0.0001

2.25 (1.62-3.14)

Serum urea (mg/dL)

≤ 27.1 mmol/L

1186 (64.2%)

641 (54.0%)

1

>27.1 mmol/L

661 (35.8%)

358 (54.2%)

(30 data missing)

MAP (mmHg)

≤ 65

1,116 (60.4%)

718 (64.3%)

>65 (28 data missing)

703 (38.1%)

260 (37.0%)

<0.0001

3.07 (2.53-3.74)

SOFA CVS score

0

270 (14.6%)

73 (27%)

SOFA ≤ 2

1

206 (11.2%)

77 (37.4%)

versus

2

494 (26.7%)

253 (51.2%)

SOFA >2

3

0

-

4

877 (47.5%)

596 (67.96%)

<0.0001

2.98 (2.47-3.61)

SOFA RESP score

0

21 (1.1%)

17 (80.95%)

1

0

-

2

225 (12.2%)

43 (19.1%)

3

0

-

4

1601 (86%)

939 (58.7%)

<0.0001

4.4 (3.23-5.98)

SOFA NEURO score

0

1352 (73.2%)

686 (50.7%)

1

68 (3.7%)

30 (44.1%)

2

109 (5.9%)

59 (54.1%)

3

145 (7.9%)

88 (60.7%)

<0.0001

2.32 (1.79-3.01)

4

173 (9.4%)

136 (78.6%)

SOFA COAG score

0

739 (40%)

368 (49.8%)

1

597 (32.3%)

331 (55.4%)

2

511 (27.7%)

300 (58.7%)

3

0

-

4

0

-

N/A

SOFA LIVER score

0

1125 (60.9%)

550 (48.9%)

1

206 (11.2%)

129 (62.6%)

2

140 (7.6%)

292 (15.8%)

3

188 (64.4%)

84 (60.0%)

4

84 (4.5%)

48 (57.1%)

0.133

1.25 (0.94-1.66)

Total SOFA score

≤ 12

1149 (62.2%)

517 (45.0%)

>12 (21 data missing)

677 (36.7%)

465 (68.7%)

<0.0001

0.37 (0.31-0.46)

Organ failure

CVS failure

689 (37.3%)

446 (64.7%)

No CVS failure

1,158 (62.7%)

553 (47.8%)

<0.0001

2.01 (1.65-2.44)

RS failure

964 (52.2%)

615 (63.8%)

No RS failure

883 (47.8%)

384 (43.5%)

<0.0001

2.29 (1.90-2.76)

GI failure

428 (23.2%)

299 (69.9%)

<0.0001

2.38 (1.89-3.00)

No GI failure

1419 (76.8%)

700 (49.3%)

NEURO failure

210 (11.4%)

160 (76.2%)

<0.0001

3.04 (2.18-4.24)

No NEURO failure

1,637 (88.6%)

839 (51.3%)

HAEM failure

180 (9.7%)

118 (65.6%)

No HAEM failure

1,667 (90.3%)

881 (52.8%)

0.0012

1.70 (1.23-2.34)

HEP failure

104 (5.6%)

80 (76.9%)

No HEP failure

1743 (94.4%)

919 (52.7%)

<0.0001

2.99 (1.88-4.76)

CVS + RS failure

352 (19.1%)

260 (73.9%)

No CVS + no RS failure

546 (29.6%)

198 (36.3%)

<0.0001

4.97 (3.70-6.67)

Total number of failed organs

0

129 (6.98%)

34 (26.4%)

1

437 (23.7%)

166 (38.0%)

2

683 (37.0%)

365 (53.4%)

3

389 (21.1%)

255 (65.6%)

>3

209 (11.3%)

179 (85.6%)