Figure 6From: Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusionSchematic diagram: relation between the release of HMGB1, complement activation and induction of an inflammatory response in the vascular endothelium early after trauma. HMGB1 = high mobility group box nuclear protein 1; RAGE: receptor for the advanced glycation end products. MAPK: mitogen-activated protein kinases.Back to article page