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Figure 4 | Critical Care

Figure 4

From: Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion

Figure 4

High plasma levels of HMGB1 are associated with increased fibrinolytic activity in trauma patients. Blood samples were obtained from 168 consecutive major trauma patients immediately upon admission to the hospital. (a to c) High plasma levels of high mobility group box nuclear protein 1 (HMGB1) are associated with increased fibrinolytic activity early after trauma, as shown by the plasma levels of plasminogen activator inhibitor-1 (PAI-1), tissue plasminogen activator (t-PA) and D-Dimers. Data are presented in quartiles, *P ≤ 0.05 based on test for rank and trend.

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Critical Care

ISSN: 1364-8535