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Table 1 Clinical characteristics of patients with sepsis due to VAP (n = 36) and sepsis caused by other infections (n = 32).

From: Decrease of CD4-lymphocytes and apoptosis of CD14-monocytes are characteristic alterations in sepsis caused by ventilator-associated pneumonia: results from an observational study

 

VAP

Other infections

P

Male/female

23/13

14/18

0.099

Age (years)

68.88 (15.57)

64.41 (19.76)

0.300

Sepsis/severe sepsis/septic shock

7/22/7

15/7/10

0.411

APACHE II score

18.25 (4.31)

15.33 (5.03)

0.200

WBCs (/μl)

11530 (1179)

14530 (1469)

0.141

   Monocytes

234 (149)

311 (49)

0.422

   Lymphocytes

629 (896)

685 (172)

0.922

   Neutrophils

8299 (1342)

9180 (1371)

0.642

Use of steroids (n, %)

12 (33.33)

13 (28.12)

0.501

Comorbidities (n, %)

   

   COPD

9 (25.00)

3 (9.38)

0.083

   DM

9 (25.00)

6 (18.75)

0.439

   CHF

3 (8.33)

7 (21.87)

0.206

   CRF

4 (11.11)

2 (6.25)

0.414

Prior infections (n)

2

1

 

Number of failing organs (n)

   

   Two or more

8

11

 

Duration of hospitalization (days)

18.93 (20.84)

19.04 (27.90)

0.151

Duration of mechanical ventilation (days)

18.34 (21.11)

26.76 (29.1)

0.525

Bacterial causes (n, %)

   

   P. aeruginosa

12 (33.33)

4 (12.50)

 

   A. baumannii

7 (19.44)

5 (15.62)

 

   K. pneumoniae

3 (8.33)

5 (15.62)

 

   E. coli

1 (2.77)

5 (15.62)

 

   Ent. cloacae

2 (5.55)

2 (6.25)

 
  1. Values are expressed as means (standard deviation).
  2. APACHE = Acute Physiology and Chronic Health Evaluation; CHF = congestive heart failure; CRF = chronic renal failure; COPD = chronic pulmonary obstructive disease; DM = diabetes mellitus; VAP = ventilator-associated pneumonia; WBCs = white blood cells.