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Table 3 Independent predictors for in-hospital mortality using Cox proportional hazards model

From: Late initiation of renal replacement therapy is associated with worse outcomes in acute kidney injury after major abdominal surgery

Variables Univariate Multivariate (Backward stepwise likelihood ratio)
  HR 95% CI P HR 95% CI P
Old age (> 65 years)a 1.960 1.127--3.408 0.017 2.090 1.196--3.654 0.010
Cardiac failureb 4.084 2.003--8.328 < 0.001 4.620 2.216--9.632 < 0.001
Pre-RRT SOFA scorec 1.138 1.054--1.228 0.001 1.152 1.065--1.247 < 0.001
CVVHd 1.940 1.123--3.352 0.018 ---- ----- -----
Late dialysise 1.852 1.081--3.170 0.025 1.846 1.071--3.182 0.027
  1. The independent variables were selected for multivariate analysis if they had a P ≤ 0.1 on univariate analysis.
  2. Data were gathered before RRT initiation. Duration in analysis is calculated from RRT initiation to end point (mortality or discharge).
  3. a hazard for patients > 65 years = 1.0; b hazard for patients without cardiac failure = 1.0; c every increment of 1 point; d hazard for patients underwent intermittent hemodialysis = 1.0; e Late dialysis denotes initiation RRT in RIFLE-R and -F, hazard for patients in early dialysis group (start RRT in RIFLE-0 and --I) = 1.0.
  4. APACHE II = Acute Physiology and Chronic Health Evaluation II; CVVH = continuous venovenous hemofiltration; HR = hazard ratio; 95% CI = 95% confidence interval; RRT = renal replacement therapy; SOFA = Sequential Organ Failure Assessment.