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Table 4 Predictive value of the cuff leak test

From: Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

  

Cuff leak cut off

     

Author

Year

Volume (ml)

Percentage of tidal volumea

Outcome

Sensitivity

Specificity

PPV

NPV

Miller and Cole [27]

1996

110

 

PES

0.67

0.99

0.80

0.98

Jaber and colleagues[30]

2003

130

12

PES

0.85

0.95

0.69

0.98

de Bast and colleagues [36]

2002

 

15.5

Reintubation

0.75

0.72

0.25

0.96

Sandhu and colleagues [26]

2000

 

10.0

PES or reintubation

0.54

0.96

0.64

0.94

Wang and colleagues [14]

2007

88

 

PES

  

0.55

0.91

Maury and colleagues [25]

2004

0

 

PES

1.00

0.80

0.15

1.00

Chung and colleagues [55]

2006

140

 

Laryngeal edema

0.89

0.90

0.84

0.93

Engoren [56]

1999

110

 

PES

0.00

0.96

0.00

0.99

Kriner and colleagues [8]

2005

110

 

PES

0.50

0.84

0.12

0.97

Cheng and colleagues [3]

2006

 

18.0

PES

0.85

0.72

0.21

0.98

  1. NPV, negative predictive value; PPV, positive predictive value; PES, post-extubation stridor. aCuff leak volume as a percentage of inspiratory or expiratory tidal volume.