|
Variable†
|
Hazard ratio
|
95% CI
|
P value
|
|---|
|
Received EGDT*
|
0.55
|
0.35-0.87
|
0.01
|
|
Lowest ED SBP
|
1.0
|
0.99-1.01
|
0.59
|
|
Highest ED RR
|
1.0
|
0.99-1.01
|
0.55
|
|
DD-ESRD**
|
1.5
|
0.95-2.3
|
0.08
|
|
Initial SOFA score
|
1.1
|
1.05-1.2
|
0.004
|
|
Received steroids***
|
1.1
|
0.7-1.7
|
0.70
|
- CI = confidence interval; DD ESRD = dialysis dependent end stage renal disease; ED = emergency department; EGDT - early goal directed therapy; RR = respiratory rate; SBP = systolic blood pressure; SOFA = sequential organ failure assessment.
- * Patients in the pre-implementation group did not receive EGDT and those in the post-implementation group did receive EGDT.
- ** Refers to patient reported diagnosis established previous to index hospitalization.
- *** Refers to patients who received systemic corticosteroids during the index hospitalization.
- † Dependent variable: one-year mortality.
-
Model Analysis
- Log likelihood with all covariates = -613.
- Deviance chi-squared = 26.9, degrees of freedom = 6, P = 0.0001.
