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Table 2 Ventilatory setting, gas exchange, respiratory mechanics and hemodynamic variables at baseline

From: Effects of positive end-expiratory pressure on respiratory function and hemodynamics in patients with acute respiratory failure with and without intra-abdominal hypertension: a pilot study

 

Normal IAP (n = 10)

IAH (n = 10)

P value

Ventilatory setting

   

VT (ml/kg IBW)

5.3 ± 0.4

5.6 ± 0.3

0.178

RR, breaths/min

18 ± 3

16 ± 3

0.129

PEEP, cmH2O

9.1 ± 1.7

9.6 ± 1.8

0.532

Gas exchange

   

PaO2/FiO2

203 ± 51

180 ± 77

0.479

PaCO2, mmHg

44 ± 9

44 ± 9

0.875

PH

7.35 ± 0.09

7.39 ± 0.05

0.234

Mechanics

   

Pplat, cmH2O

23 ± 4

24 ± 4

0.623

Pes insp, cmH2O

18 ± 4

19 ± 3

0.378

Pes exp, cmH2O

12 ± 3

13 ± 4

0.554

Ptranspul insp, cmH2O

9 ± 5

8 ± 4

0.796

Ptranspul exp, cmH2O

0 ± 3

-1 ± 3

0.760

Estat, RS, cmH2O/l

32.3 ± 8.8

33.4 ± 8.7

0.774

Estat, L, cmH2O/l

20 ± 8.8

20 ± 7.6

0.988

Estat, CW, cmH2O/l

12.3 ± 3.7

13.4 ± 5.4

0.567

VexhaledZEEP, ml

236 ± 139

185 ± 98

0.402

Hemodynamics

   

HR, beats/min

89 ± 26

82 ± 24

0.545

MAP, mmHg

80 ± 13

76 ± 7

0.463

CI, l/min/m2

4.5 ± 1.6

3.4 ± 1.1

0.097

ITBVI, ml/m2

991 ± 334

1060 ± 163

0.562

EVLWI, ml/m2

10.7 ± 5.7

6.7 ± 1.9

0.059

  1. Estat, CW = static chest wall elastance; Estat, L = static lung elastance; Estat, RS = static respiratory system elastance; EVLWI = extravascular lung water index; FiO2 = fraction of inspired oxygen; HR = heart rate; IAH = intra-abdominal hypertension; IAP = intra-abdominal pressure; IBW = ideal body weight; ITBVI = intrathoracic blood volume index; MAP = mean arterial pressure; PaCO2 = partial pressure of arterial carbon dioxide; PEEP = positive end-expiratory pressure; Pes insp = inspiratory esophageal pressure; Pes exp = expiratory esophageal pressure; Pplat = inspiratory plateau pressure; Ptranspulexp = expiratory transpulmonary pressure; Ptranspul insp = inspiratory transpulmonary pressure; RR = respiratory rate; Vexhaled ZEEP = exhaled volume from PEEP to zero end-expiratory pressure; VT = tidal volume.
  2. Data are presented as mean ± standard deviation.