Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study

Torgersen, Christian; Schmittinger, Christian A; Wagner, Sarah; Ulmer, Hanno; Takala, Jukka; Jakob, Stephan M; Dünser, Martin W

doi:10.1186/cc8114

Critical Care

Table 5 Association between different cardiac index/cardiac power index levels and 28-day mortality

From: Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study

	n (%)	AUC ROC	Sens (%)	Spec (%)	PPV (%)	NPV (%)	RR	95% Con Int
HP between different CI levels
HTI of CI drops <3.75 l/min/m²	92 (100)	0.80	42.9	90.5	66.7	78.1	0.98	0.96-1.00
HTI of CI drops <3.50 l/min/m²	92 (100)	0.80	42.9	90.5	66.7	78.1	0.98	0.96-1.00
HTI of CI drops <3.25 l/min/m²	92 (100)	0.80	42.9	90.5	66.7	78.1	0.98	0.96-1.00
HTI of CI drops <3.00 l/min/m²	92 (100)	0.81	46.4	92.1	72.2	79.5	1.04	1.01-1.07
HTI of CI drops <2.75 l/min/m²_	87 (94.6)	0.80	46.4	92.1	72.2	79.5	1.04	1.01-1.08
HTI of CI drops <2.50 l/min/m²	84 (91.3)	0.79	39.3	92.1	68.6	77.3	1.05	1.00-1.10
HTI of CI drops <2.25 l/min/m²	73 (79.3)	0.78	39.3	92.1	68.8	77.3	1.06	0.99-1.14
HTI of CI drops <2.00 l/min/m²	58 (63)	0.77	35.7	90.5	62.5	76.0	1.11	0.96-1.27
HTI of CI drops <1.75 l/min/m²	38 (41.3)	0.77	39.3	93.7	73.3	77.6	1.34	0.95-1.89
HTI of CI drops <1.50 l/min/m²	22 (23.9)	0.76	32.1	92.1	64.3	75.3	1.46	0.69-3.10
HP below different CPI levels
HTI of CPI drops <1.2 W/m²	92 (100)	0.81	39.3	88.9	61.1	76.7	0.86	0.75-0.98
HTI of CPI drops <1.1 W/m²	92 (100)	0.81	39.3	88.9	61.1	76.7	0.86	0.75-0.98
HTI of CPI drops <1.0 W/m²	92 (100)	0.81	39.3	88.9	61.1	76.7	0.86	0.75-0.98
HTI of CPI drops <0.9 W/m²	92 (100)	0.81	39.3	88.9	61.1	76.7	0.86	0.75-0.98
HTI of CPI drops <0.8 W/m²	92 (100)	0.81	39.3	88.9	61.1	76.7	1.16	1.01-1.33
HTI of CPI drops <0.7 W/m²	92 (100)	0.80	39.3	88.9	61.1	76.7	1.16	1.01-1.33
HTI of CPI drops <0.6 W/m²	91 (98.9)	0.80	39.3	88.9	61.1	76.7	1.16	1.01-1.33
HTI of CPI drops <0.5 W/m²	91 (98.9)	0.79	39.3	90.5	64.7	77.0	1.17	1.00-1.35
HTI of CPI drops <0.4 W/m²	91 (98.9)	0.79	39.3	90.5	64.7	77.0	1.20	0.98-1.47
HTI of CPI drops <0.3 W/m²	69 (75)	0.78	35.7	92.1	66.7	76.3	1.46	0.86-2.47

Single Receiver Operating Characteristic Curve Models were based on logistic regression models adjusted for age, admission year, mean catecholamine (epinephrine, norepinephrine, dobutamine, and milrinone) dosages and disease severity as assessed by the Simplified Acute Physiology Score II (excl. heart rate and systolic arterial blood pressure counts).
AUC ROC = area under the receiver operating characteristic curve; CI = cardiac index; Con Int = confidence interval; CPI = cardiac power index; HTI = hourly time integral; NPV = negative predictive value; PPV = positive predictive value; RR = relative risk; Sens = sensitivity; Spec = specificity.

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ISSN: 1364-8535

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