Skip to main content

Table 1 Patient characteristics by cohort

From: Candidemia on presentation to the hospital: development and validation of a risk score

  Number of admissions (% of total)  
Characteristic Derivation cohort (n = 64,019) Validation cohort (n = 24,685) P value
Candidemia 738 (1.2) 321 (1.3) 0.0697
Demographics    
   Age < 65 years 19,523 (30.5) 8403 (34.0) < 0.0001
   Men 29,845 (46.6) 12,090 (49.0) < 0.0001
   Mortality 9664 (15.1) 3173 (12.9) < 0.0001
Laboratory findings    
   Albumin ≤ 1.8 g/dL 2704 (4.2) 1278 (5.2) < 0.0001
   Albumin 1.9--2.2 g/dL 3800 (5.9) 1757 (7.1) < 0.0001
   Arterial pH ≤ 7.36 5913 (9.2) 2684 (10.9) < 0.0001
   Potassium > 5.6 mEq/dL 3133 (4.9) 1182 (4.8) 0.5150
   Sodium > 145 mEq/dL 3600 (5.6) 1206 (4.9) < 0.0001
   Bands > 32% 5345 (8.4) 1813 (7.4) < 0.0001
   White blood cells > 27,000/mm3 5096 (8.0) 1980 (8.0) 0.7604
Vital signs and mental status    
   Temperature ≤ 98°F 16,917 (26.4) 4780 (19.4) < 0.0001
   Severe altered mental statusa 6301 (9.8) 2255 (9.1) 0.0014
   Temperature ≤ 98°F or severe altered mental status 21,140 (33.0) 6454 (26.1) < 0.0001
History and severe comorbidities    
   Metastatic cancer 3245 (5.1) 1262 (5.1) 0.7910
   Tumor 2693 (4.2) 1136 (4.6) 0.0094
   Cachexiab 4549 (7.1) 2392 (9.7) < 0.0001
Other variables    
   Prior-admission within 30 days 11,215 (17.5) 4603 (18.7) < 0.0001
   Admitted from other healthcare facility 12,813 (20.0) 5581 (22.6) < 0.0001
   Mechanical ventilation at admission 5864 (9.2) 2695 (10.9) < 0.0001
  1. aSevere altered mental status defined as Glasgow Coma Scale less than 5 or a designation of coma by a physician.
  2. bCachexia defined by ICD-9 secondary diagnosis code.