| |
Severe sepsis
|
Sepsis without organ failure
|
Control
|
P valuea
|
|---|
|
N
|
54
|
31
|
45
| |
|
Age
b
|
52.4 (48.3-56.5)
|
50.8 (46.5-55.2)
|
47.2 (43.1-51.4)
|
NS
|
|
Male n (%)
|
33 (61)
|
21 (68)
|
30 (67)
|
NS
|
|
Diabetic n (%)
|
18 (33)
|
7 (23)
|
14 (31)
|
NS
|
|
Smoker n (%)
|
28 (57)
|
12 (39)
|
18 (41)
|
NS
|
|
IHD n (%)
|
9 (17)
|
6 (19)
|
6 (13)
|
NS
|
|
On statin n (%)
|
13 (24)
|
9 (29)
|
13 (29)
|
NS
|
|
APACHE II
c
|
19.0 (15-23)
|
7.5 (5-11)
| |
< 0.0001
|
|
SOFA score
c
|
6 (3-9)
|
1 (0-2)
| |
< 0.0001
|
|
Focus of infection -- n (%)
| | | | |
|
Pleuropulmonary n (%)
|
26 (48)
|
16 (52)
| | |
|
Skin/soft tissue n (%)
|
9 (17)
|
9 (29)
| | |
|
Intra-abdominal n (%)
|
6 (11)
|
1 (3)
| | |
|
Urinary n (%)
|
4 (7)
|
3 (10)
| | |
|
Other n (%)
|
9 (17)
|
2(6)
| | |
|
Causative organism
| | | | |
|
None cultured n (%)
|
25 (46)
|
20 (65)
| | |
|
Gram positive bacterium n (%)
|
15 (28)
|
5 (16)
| | |
|
Gram negative bacterium n (%)
|
14 (26)
|
6 (19)
| | |
|
Origin of sepsis
| | | | |
|
Community-acquired n (%)
|
47 (87)
|
30 (97)
| | |
|
Nosocomial n (%)
|
7 (13)
|
1 (3)
| | |
- a. For difference between all three groups by one way analysis of variance
- b. Mean (95% confidence interval)
- c. Median (interquartile range)
- APACHE II = Acute Physiology and Chronic Health Evaluation II; IHD = ischaemic heart disease; NS = not significant; SOFA = Sequential Organ Failure Assessment score
