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Table 4 Exposures associated with in-hospital mortality in 520 patients with ALI

From: Mortality in sepsis versus non-sepsis induced acute lung injury

  Univariable* Multivariable*
Exposure Odds ratio
(95% CI)
P value Odds ratio
(95% CI)
P value
Age, years 1.03 (1.02-1.04) <0.0001 1.04 (1.02-1.05) <0.001
Ethnicity 0.98 (0.69-1.4) 0.93   
Medical ICU 2.08 (1.32-3.30) 0.002 2.76(1.42-5.36) 0.003
ICU LOS prior to ALI diagnosis 1.09 (1.01-1.19) 0.025 1.15 (1.03-1.29) 0.014
Hospital LOS prior to ALI diagnosis 1.03 (1.01-1.06) 0.008 1.03 (0.99-1.05) 0.06
APACHE II at ICU admission 1.08 (1.06-1.11) <0.0001 1.05 (1.02-1.08) 0.003
Lung Injury Score at ALI diagnosis 2.23 (1.77-2.81) <0.0001 2.33 (1.74-3.12) <0.001
SOFA at ALI diagnosis 1.26 (1.19-1.33) <0.0001 1.17 (1.09-1.25) <0.001
PEEP at day 1 after ALI, cmH20 1.14 (1.09-1.19) <0.0001 1.04 (0.98-1.10) 0.15
Cumulative fluid balance in first 7 days after ALI diagnosis, Liters 1.06 (1.04-1.09) <0.0001 1.06 (1.03-1.09) <0.001
Sepsis vs. non-sepsis ALI risk factor 2.06 (1.37-3.09) 0.001 1.02 (0.59-1.76) 0.61
  1. * Calculated using logistic regression analysis. The odds ratio indicates the increased odds of in-hospital mortality for a one unit increase in each continuous exposure variable or for sepsis vs. non-sepsis for this binary exposure variable.
  2. ALI = acute lung injury; APACHE = Acute Physiology and Chronic Health Evaluation; CI = confidence interval; ICU = intensive care unit; LOS = length of stay; PEEP = positive end-expiratory pressure; SOFA = Sequential Organ Failure Assessment.