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Table 4 Exposures associated with in-hospital mortality in 520 patients with ALI

From: Mortality in sepsis versus non-sepsis induced acute lung injury

 

Univariable*

Multivariable*

Exposure

Odds ratio

(95% CI)

P value

Odds ratio

(95% CI)

P value

Age, years

1.03 (1.02-1.04)

<0.0001

1.04 (1.02-1.05)

<0.001

Ethnicity

0.98 (0.69-1.4)

0.93

  

Medical ICU

2.08 (1.32-3.30)

0.002

2.76(1.42-5.36)

0.003

ICU LOS prior to ALI diagnosis

1.09 (1.01-1.19)

0.025

1.15 (1.03-1.29)

0.014

Hospital LOS prior to ALI diagnosis

1.03 (1.01-1.06)

0.008

1.03 (0.99-1.05)

0.06

APACHE II at ICU admission

1.08 (1.06-1.11)

<0.0001

1.05 (1.02-1.08)

0.003

Lung Injury Score at ALI diagnosis

2.23 (1.77-2.81)

<0.0001

2.33 (1.74-3.12)

<0.001

SOFA at ALI diagnosis

1.26 (1.19-1.33)

<0.0001

1.17 (1.09-1.25)

<0.001

PEEP at day 1 after ALI, cmH20

1.14 (1.09-1.19)

<0.0001

1.04 (0.98-1.10)

0.15

Cumulative fluid balance in first 7 days after ALI diagnosis, Liters

1.06 (1.04-1.09)

<0.0001

1.06 (1.03-1.09)

<0.001

Sepsis vs. non-sepsis ALI risk factor

2.06 (1.37-3.09)

0.001

1.02 (0.59-1.76)

0.61

  1. * Calculated using logistic regression analysis. The odds ratio indicates the increased odds of in-hospital mortality for a one unit increase in each continuous exposure variable or for sepsis vs. non-sepsis for this binary exposure variable.
  2. ALI = acute lung injury; APACHE = Acute Physiology and Chronic Health Evaluation; CI = confidence interval; ICU = intensive care unit; LOS = length of stay; PEEP = positive end-expiratory pressure; SOFA = Sequential Organ Failure Assessment.