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Table 1 Total cell and neutrophil counts in bronchoalveolar lavage fluid

From: Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats

 

Total cells

Neutrophils

MPO

Controls

21 (19-24)

0 (0-0)

32 (20-59)

Streptococcus pneumoniae pneumonia (t = 40 hours)

   Placebo

171 (92-206)

73 (39-112)

99 (53-106)

   rh-aPC

208 (122-233)

86 (56-104)

186 (66-265)

   AT

36 (23-38)*

1 (0-5)**

68 (24-74)

   Heparin

417 (313-579)

92 (69-114)

498 (224-932)*

   Danaparoid

542 (462-681)

111 (99-125)

407 (167-535)

  1. Cell counts 40 hours after bacterial challenge (Streptococcus pneumoniae, serotype 3, ATCC 6303). Controls are uninfected rats (n = 4). Total cell and neutrophil data are expressed as median (interquartile range) × 104 per milliliter of bronchoalveolar lavage fluid. Myeloperoxidase (MPO) is expressed as pg/mL lung homogenate median (interquartile range). (* P < 0.05;** P < 0.01 versus placebo according to Kruskal-Wallis and Dunn's post-tests).
  2. rh-aPC = recombinant human activated protein C; AT = antithrombin.
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Critical Care

ISSN: 1364-8535