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Figure 2 | Critical Care

Figure 2

From: Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats

Figure 2

Systemic coagulation and fibrinolysis. The effects of anticoagulants nebulized into the lungs of rats on plasma levels of (a) thrombin-antithrombin complexes (TATc) and (b) systemic plasminogen activator activity (PAA), 40 hours after intra-tracheal bacterial challenge. Dotted lines stipulate the normal values in healthy animals and untreated animals with pneumonia. Data represent mean ± standard deviation. * P < 0.01 vs. placebo. APC = recombinant-human activated protein C; AT = plasma = derived human antithrombin; Hep = heparin; Dan = danaparoid.

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