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Table 5 Multivariate logistic regression analysis for admissions to critical care units with haematological malignancya

From: Admission factors associated with hospital mortality in patients with haematological malignancy admitted to UK adult, general critical care units: a secondary analysis of the ICNARC Case Mix Programme Database

 

Number of admissions

Number of deaths

Percentage of deaths

Adjusted

    

Odds ratio (95% CI)

P value

Serum potassium

     

   <3.0 mmol/l

63

45

71.4

2.40 (1.02 to 5.67)

0.226

   3.0 to 3.4 mmol/l

274

169

61.7

1.29 (0.87 to 1.92)

 

   3.5 to 5.4 mmol/l

5,548

3,124

56.3

Reference

 

   5.5 to 5.9 mmol/l

431

303

70.3

0.93 (0.69 to 1.27)

 

   6.0 to 6.9 mmol/l

343

260

75.8

1.12 (0.79 to 1.61)

 

   7.0+ mmol/l

106

83

78.3

0.79 (0.40 to 1.53)

 

Serum urea

    

<0.001

   <6.2 mmol/l

1,315

504

38.3

1.05 (0.78 to 1.42)

 

   6.2 to 7.1 mmol/l

422

189

44.8

Reference

 

   7.2 to 14.3 mmol/l

2,158

1,272

58.9

1.45 (1.09 to 1.93)

 

   14.4+ mmol/l

2,283

1,666

73.0

2.39 (1.74 to 3.28)

 

Serum creatinine

    

0.310

   <0.6 μmol/l

193

94

48.7

1.41 (0.94 to 2.13)

 

   0.6 to 1.4 μmol/l

3,104

1,510

48.7

Reference

 

   1.5+ μmol/l

3,359

2,302

68.5

0.84 (0.70 to 1.02)

 

Urine output

    

< 0.001

   <400 ml/day

1,121

956

85.3

2.91 (2.23 to 3.79)

 

   400 to 599 ml/day

297

239

80.5

2.66 (1.76 to 4.00)

 

   600 to 899 ml/day

488

341

69.9

2.05 (1.53 to 2.75)

 

   900 to 1,499 ml/day

1,270

752

59.2

1.58 (1.30 to 1.91)

 

   1,500 to 1,999 ml/day

984

515

52.3

1.37 (1.13 to 1.66)

 

   2,000+ ml/day

2,689

1,229

45.7

Reference

 

Haematocrit

    

0.001

   <20%

171

119

69.9

3.22 (0.96 to 10.85)

 

   20 to 29%

3,073

1,904

62.0

4.56 (1.51 to 13.80)

 

   30 to 45%

3,405

1,897

55.7

3.69 (1.22 to 11.13)

 

   46 to 49%

55

28

50.9

2.13 (0.58 to 7.82)

 

   50 to 59%

26

10

38.5

Reference

 

   60+%

5

3

60.0

1.24 (0.09 to 17.20)

 

Lowest white blood cell count

    

0.425

   <1 × 109/l

1,217

799

65.7

1.17 (00.95 to 1.45)

 

   1 to 2 × 109/l

820

503

61.3

1.15 (0.92 to 1.43)

 

   3 to 14 × 109/l

3,009

1,605

53.3

Reference

 

   15 to 39 × 109/l

1,039

616

59.3

0.98 (0.80 to 1.20)

 

   40+ × 109/l

459

301

65.6

1.16 (0.86 to 1.56)

 

Glasgow Coma Score

    

< 0.001

   3

511

437

85.5

3.32 (2.33 to 4.74)

 

   4

29

21

72.4

1.58 (0.55 to 4.52)

 

   5

30

22

73.3

2.20 (0.85 to 5.73)

 

   6

81

54

66.7

1.47 (0.80 to 2.71)

 

   7 to 13

595

392

65.9

1.80 (1.40 to 2.31)

 

   14

376

223

59.3

1.48 (1.11 to 1.98)

 

   15

3,190

1,385

43.4

Reference

 

   Sedated

1,518

1,119

73.7

1.85 (1.50 to 2.28)

 

   Sedated and paralysed

214

173

80.8

2.40 (1.51 to 3.82)

 

Mechanical ventilation

    

0.154

   No

3,169

1,435

45.3

Reference

 

   Yes

3,970

2,788

70.2

1.53 (0.85 to 2.73)

 

Severe sepsis

    

0.001

   No

3,245

1,630

50.2

Reference

 

   Yes

3,916

2,609

66.6

1.29 (1.10 to 1.50)

 

CPR within 24 hours prior to admission

    

0.317

   No

6,728

3,884

57.7

Reference

 

   Yes

426

353

82.9

1.21 (0.84 to 1.74)

 

Hospital length of stay before ICU admission

    

< 0.001

   0 days

1,358

735

54.1

1.02 (1.01 to 1.02)

 

   1 day

1,266

614

48.5

(per day)

 

   2 to 4 days

1,253

690

55.1

  

   5 to 9 days

977

617

63.2

  

   10 to 19 days

1,109

735

66.3

  

   >20 days

1,195

846

70.8

  
  1. aAnalysis of the effect of serum potassium, urea, creatinine, urine output, haematocrit, white cell count, Glasgow Coma Score, invasive ventilation, severe sepsis, cardiopulmonary resuscitation (CPR) and length of hospital stay prior to intensive care admission on outcome. CI: confidence interval; ICU: intensive care unit.