| AML (n = 622) | ALL (n = 272) | CMLL (n = 310) |  |
---|---|---|---|---|
Age, mean (SD) | 49.8 (16.8) | 33.5 (20.1) | 61.7 (16.1) | Â |
Male, n (%) | 331 (53.2) | 143 (52.6) | 205 (66.1) | Â |
APACHE II Acute Physiology Score, mean (SD) | 20.1 (6.9) | 18.6 (6.9) | 17.2 (6.9) | Â |
APACHE II score, mean (SD) | 26.3 (7.6) | 23.8 (7.2) | 24.9 (7.6) | Â |
ICNARC physiology score, mean (SD) | 26.5 (11.1) | 24.1 (11.2) | 23.7 (11.4) | Â |
Number of organ system failures, mean (SD) | 1.9 (1.2) | 1.7 (1.1) | 1.5 (1.1) | Â |
Mechanically ventilated at any time during first 24 hours in the ICU, n (%) | 329 (53.1) | 129 (47.6) | 165 (53.4) | Â |
Severe sepsis, n (%) | 284 (45.7) | 121 (44.5) | 137 (44.2) | Â |
Physiology | Â | Â | Â | Â |
   Lowest platelet count (× 109/l), median (IQR) | 26 (13 to 51) | 34 (19 to 62) | 61 (34 to 121) |  |
   Lowest white blood cell count (× 109/l), median (IQR) | 2.3 (0.2 to 16.1) | 1.9 (0.2 to 6.8) | 10.3 (3.1 to 34.6) |  |
Mortality, n (%) | Â | Â | Â | Â |
   Unit | 341 (54.8) | 116 (42.7) | 126 (40.7) |  |
   Acute hospitala | 398 (67.3) | 141 (55.5) | 165 (56.9) |  |
Unit length of stay (days), median (IQR) | Â | Â | Â | Â |
   Unit survivor | 2.8 (1.0 to 5.6) | 2.2 (1.0 to 4.9) | 2.2 (1.0 to 6.1) |  |
   Unit nonsurvivor | 1.5 (0.6 to 4.4) | 3.4 (1.0 to 10.2) | 1.5 (0.4 to 6.3) |  |
   All | 1.9 (0.8 to 5.3) | 2.6 (1.0 to 6.7) | 1.9 (0.8 to 6.1) |  |
Acute hospital length of stay (days)a, median (IQR) | Â | Â | Â | Â |
   Hospital survivor | 38 (27 to 62) | 39 (21 to 61) | 19 (11 to 41) |  |
   Hospital nonsurvivor | 15 (3 to 27) | 23 (8 to 45) | 9 (3 to 24) |  |
   All | 22 (8 to 39) | 29 (13 to 51) | 15 (7 to 33) |  |
Readmission within the same acute hospital stay, n (%) | 28 (4.5) | 14 (5.2) | 18 (5.8) | Â |
Acute hospital mortality by number of organ system failures, n (%) | Â | Â | Â | Â |
   0 organ failures | 24 (47.1) | 10 (27.8) | 16 (29.6) |  |
   1 organ failure | 99 (54.4) | 39 (48.2) | 51 (45.5) |  |
   2 organ failures | 114 (65.9) | 49 (60.5) | 44 (67.7) |  |
   3 organ failures | 105 (85.4) | 31 (79.5) | 38 (90.5) |  |
   4 organ failures | 47 (88.7) | 9 (64.3) | 15 (93.8) |  |
   5 organ failures | 9 (100.0) | 3 (100.0) | 1 (100.0) |  |
 | Hodgkin's lymphoma (n = 216) | Non-Hodgkin's lymphoma (n = 1,007) | Bone marrow transplant (n = 156) | Myeloma (n = 397) |
Age, mean (SD) | 50.7 (17.9) | 56.3 (15.8) | 40.8 (14.7) | 63.0 (11.2) |
Male, n (%) | 123 (56.9) | 611 (60.7) | 83 (53.2) | 244 (61.5) |
APACHE II Acute Physiology Score, mean (SD) | 16.7 (7.0) | 17.2 (7.4) | 18.5 (8.6) | 17.1 (7.5) |
APACHE II score, mean (SD) | 23.2 (7.5) | 24.1 (8.0) | 23.4 (9.5) | 24.3 (7.9) |
ICNARC physiology score, mean (SD) | 23.2 (11.0) | 24.0 (10.9) | 24.0 (12.4) | 24.2 (10.8) |
Number of organ system failures, mean (SD) | 1.5 (1.2) | 1.5 (1.2) | 1.7 (1.3) | 1.7 (1.3) |
Mechanically ventilated at any time during first 24 hours in the ICU, n (%) | 115 (53.5) | 528 (52.7) | 69 (45.1) | 209 (52.8) |
Severe sepsis, n (%) | 101 (46.8) | 414 (41.1) | 68 (43.6) | 146 (36.8) |
Physiology | Â | Â | Â | Â |
   Lowest platelet count (× 109/l), median (IQR) | 75 (29 to 188) | 82 (33 to 184) | 37 (19 to 62) | 95 (47 to 161) |
   Lowest white blood cell count (× 109/l), median (IQR) | 6.1 (2.1 to 10.5) | 6.3 (1.8 to 13.6) | 3.7 (0.6 to 8.2) | 4.7 (1.9 to 8.8) |
Mortality, n (%) | Â | Â | Â | Â |
   Unit | 119 (55.1) | 492 (48.9) | 74 (47.4) | 151 (38.0) |
   Acute hospitala | 142 (71.0) | 625 (66.2) | 93 (65.0) | 227 (60.1) |
Unit length of stay (days), median (IQR) | Â | Â | Â | Â |
   Unit survivor | 2.7 (1.2 to 5.4) | 2.9 (1.3 to 6.7) | 2.6 (1.1 to 8.3) | 2.9 (1.2 to 8.1) |
   Unit nonsurvivor | 4.5 (1.2 to 8.7) | 2.7 (0.9 to 6.4) | 3.9 (1.1 to 7.7) | 2.8 (0.7 to 7.4) |
   All | 3.4 (1.2 to 7.2) | 2.7 (1.1 to 6.4) | 3.0 (1.1 to 7.9) | 2.9 (1.1 to 7.7) |
Acute hospital length of stay (days)a, median (IQR) | Â | Â | Â | Â |
   Hospital survivor | 24 (12 to 44) | 29 (15 to 53) | 32 (17 to 63) | 34 (18 to 55) |
   Hospital nonsurvivor | 15 (6 to 26) | 15 (6 to 30) | 28 (13 to 46) | 14 (5 to 25) |
   All | 17 (8 to 35) | 19 (9 to 35) | 29 (15 to 54) | 20 (9 to 38) |
Readmission within the same acute hospital stay, n (%) | 16 (7.4) | 59 (5.9) | 11 (7.1) | 10 (2.5) |
Acute hospital mortality by number of organ system failures, n (%) | Â | Â | Â | Â |
   0 organ failures | 26 (54.2) | 90 (43.7) | 6 (25.0) | 24 (32.4) |
   1 organ failure | 43 (71.7) | 182 (60.3) | 27 (62.8) | 54 (49.1) |
   2 organ failures | 38 (70.4) | 197 (75.2) | 28 (71.8) | 70 (68.0) |
   3 organ failures | 24 (88.9) | 102 (87.9) | 13 (72.2) | 41 (77.4) |
   4 organ failures | 10 (100.0) | 41 (93.2) | 17 (100.0) | 27 (100.0) |
   5 organ failures | 1 (100.0) | 13 (92.9) | 2 (100.0) | 11 (100.0) |