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Table 2 Demographic data and clinical characteristics grouped according to adrenal function

From: Critical illness-related corticosteroid insufficiency in patients with severe acute biliary pancreatitis: a prospective cohort study

  All patients
(n = 32)
Adrenal insufficiency
(n = 11)
Normal adrenal function
(n = 21)
P value
Age (years) 68 (55 to 80) 73 (58 to 80) 68 (55 to 81) NS (0.685)
Gender (M/F) 12/20 4/7 8/13 NS (0.923)
ICU mortality (%) 6 (18.8) 5 (45.5) 1 (4.8) 0.011
Hospital mortality (%) 7 (21.9) 5 (45.5) 2 (9.5) 0.032
BUN (mg/dl) 15.5 (10.5 to 36.5) 23 (12 to 45) 15 (8.5 to 23.5) NS (0.293)
Serum creatinine (mg/dl) 1.1 (0.6 to 1.9) 2.5 (1.1 to 3.7) 0.9 (0.6 to 1.3) 0.003
Bilirubin (mg/dl) 1.6 (0.8 to 3.2) 5.1 (1.9 to 9.6) 1.4 (0.7 to 2.0) 0.004
Albumin (g/l) 2.8 (2.4 to 3) 2.8 (2.4 to 2.8) 2.8 (2.2 to 3.1) NS (0.839)
INR 1.2 (1.2 to 1.4) 1.3 (1.2 to 1.5) 1.2 (1.2 to 1.3) NS (0.568)
MAP (mmHg) 79 (60 to 90) 58 (57 to 60) 84 (79 to 93) < 0.001
SOFA score on the day of SST 5 (3 to 9) 11 (7 to 15) 4 (2 to 6) < 0.001
APACHE II score on the day of SST 15 (10 to 20) 20 (10 to 27) 15 (11 to 18) 0.018
Ranson score 5 (3 to 6) 7 (5 to 9) 4 (3 to 5) < 0.001.
Necrosis (%) 20 (62.5) 11 (100) 9 (42.9) 0.002
Bacteremia (%) 14 (43.8) 9 (81.8) 5 (23.8) 0.003
Number of organ dysfunction on the day of SST 2 (1 to 3) 4 (2.5 to 5) 1 (1 to 2) < 0.001
   Respiratory dysfunction (%) 23 (71.9) 9 (81.8) 14 (66.7) NS (0.441)
   Coagulation dysfunction (%) 7 (21.9) 7 (63.6) 0 (0) < 0.001
   CV dysfunction (%) 10 (31.3) 9 (81.8) 1 (4.8) < 0.001
   CNS dysfunction (%) 14 (43.8) 6 (54.5) 8 (38.1) NS (0.465)
   Renal dysfunction (%) 12 (37.5) 7 (63.6) 5 (23.8) 0.027
  1. APACHE = Acute Physiology and Chronic Health Evaluation; BUN = blood urea nitrogen; CIRCI = critical illness related corticosteroid insufficiency; CNS = central nervous system; CV = cardiovascular; F = female; ICU = intensive care unit; INR = international normalized ratio; M = male; MAP = mean arterial pressure; NS = not significant; SOFA = sequential organ failure assessment; SST = short corticotropin stimulation test.