S-100B and neuron-specific enolase as predictors of neurological outcome in patients after cardiac arrest and return of spontaneous circulation: a systematic review

Table 1 Comparison of values for biomarkers between dead and alive

Authors	Year	Ref	n	on admission	Day 1	24 hours	Day 2	48 hours	Day 3
NSE
Grubb and colleagues	2007	[14]	143	-	P < 0.01	-	P < 0.01	-	-
Auer and colleagues	2006	[24]	17	NS	NS	-	P < 0.05	-	-
S-100B
Grubb and colleagues	2007	[14]	143	-	P < 0.01	-	P < 0.01	-	-
Bottiger and colleagues	2001	[18]	66	NM	-	NM	-	NM	-
Rosen and colleagues	1998	[20]	41	-	P < 0.01	-	P < 0.01	-	P < 0.01

NM = not mentioned for statistical comparison; NS = not significance; NSE = neuron specific enolase; Ref = references.

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