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Table 2 Monocyte and dendritic cell subsets

From: Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis

Monocyte or dendritic cell subset

Surface marker expression

Properties

Classical monocytes

CD14brightCD16negative

Majority of circulating monocytes [27–29]9

Inflammatory monocytes

CD14brightCD16positive

Produce high level of proinflammatory cytokines, increased in sepsis [27–29]

Dendritic cell-like monocytes

CD14dimCD16positive

Morphological and functional similarities to dendritic cells [42, 43]

Plasmacytoid dendritic cells

lin1 -CD123+HLA-DR+

Produce high level of IFNα in response to viruses [31–35]

Myeloid dendritic cells

lin1 -CD33+HLA-DR+

Potent antigen-presenting cells [31–35]

  1. lin1, lineage marker.