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Figure 3 | Critical Care

Figure 3

From: Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis

Figure 3

Cytokine production after stimulation of blood from sepsis patients using different Toll-like receptor ligands. Cytokine production after stimulation of whole blood and peripheral blood mononuclear cells from patients with sepsis using different Toll-like receptor ligands. (a) Blood was drawn from healthy controls or patients at the indicated time points (baseline, day 28) and stimulated for 6 hours with lipopolysaccharide (LPS) or lipoteichoic acid (LTA). Cytokine levels were measured in the supernatants by ELISA and were normalized to monocyte counts. (b) Simultaneously, peripheral blood mononuclear cells were stimulated with either class A (2336) or class C (2395) oligonucleotides (ODN). After 24 hours, the concentration of IFNα in the supernatants was determined using ELISA. *P < 0.05, **P < 0.01.

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Critical Care

ISSN: 1364-8535