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Table 4 Parameters of systemic NO and cytokine production in the control (n = 12, n = 11 at 24 hours of peritonitis) and AVP (n = 12) groups

From: Comparison of cardiac, hepatic, and renal effects of arginine vasopressin and noradrenaline during porcine fecal peritonitis: a randomized controlled trial

  

Before peritonitis

12 hours peritonitis

18 hours peritonitis

24 hours peritonitis

Exhaled NO (pmol/kg/min)

Control

6 (3 to 47)

22 (6 to 72)b

27 (11 to 98)b

15 (14 to 141)b

 

AVP

5 (4 to 9)

14 (7 to 17)b

12 (9 to 16)b

8 (6 to 10)a

Arterial NO3-+NO2- (μmol/gprotein)

Control

0.5 (0.4 to 1.6)

1.5 (0.6 to 2.1)b

1.8 (0.9 to 2.6)b

1.8 (1.3 to 2.7)b

 

AVP

1.0 (0.6 to 1.3)

1.4 (1.0 to 2.2)b

1.3 (1.0 to 2.4)b

1.2 (1.0 to 2.3)b

Tumor necrosis factor-α (μmol/gprotein)

Control

3 (2 to 3)

10 (8 to 16)b

20 (12 to 25)b

27 (15 to 55)b

 

AVP

2 (2 to 3)

8 (7 to 11)b

14 (12 to 19)b

18 (15 to 29)b

Interleukin 6 (μmol/gprotein)

Control

1 (1 to 1)

125 (56 to 286)b

549 (252 to 1624)b

753 (559 to 3443)b

 

AVP

1 (0 to 3)

83 (51 to 150)b

216 (119 to 365)a, b

354 (140 to 677)a, b

  1. All data are median (quartiles). a P < 0.05 between norepinephrine- and AVP-treated animals; b P < 0.05 within groups versus before peritonitis. AVP = arginine vasopressin; NO = nitric oxide.