Table 2 Parameters of systemic gas exchange, metabolism and acid-base status in the control (n = 12, n = 11 at 24 hours of peritonitis) and AVP (n = 12) groups

Arterial PO₂

Control

166 (160 to 179)

144 (124 to 153)^b

106 (93 to 121)^b

87 (80 to 114)^b

(mmHg)

AVP

163 (154 to 179)

144 (128 to 170)^b

124 (96 to 150)^b

96 (84 to 138)^b

Arterial PCO₂

Control

37 (35 to 39)

41 (40 to 44)^b

41 (39 to 45)^b

44 (39 to 46)^b

(mmHg)

AVP

36 (34 to 40)

40 (39 to 43)^b

41 (38 to 44)^b

42 (39 to 45)^b

Extravascular lung water

Control

4.4 (3.0 to 6.0)

4.8 (1.5 to 7.0)

5.8 (1.4 to 8.6)

7.4 (5.5 to 8.6)^b

(mL/kg)

AVP

3.3 (2.7 to 5.0)

7.4 (1.8 to 9.6)^b

9.0 (1.1 to 11.0)^b

5.9 (3.4 to 8.4)^b

Systemic O₂ delivery

Control

10 (9 to 11)

14 (11 to 18)^b

19 (16 to 23)^b

17 (12 to 21)^b

(mL/kg/min)

AVP

11 (10 to 12)

11 (11 to 13)

12 (8 to 15)^a

13 (10 to 16)

Systemic O₂ uptake

Control

4.9 (4.0 to 5.3)

4.4 (3.7 to 5.7)

6.0 (4.5 to 7.2)^b

6.0 (5.3 to 6.8)^b

(mL/kg/min)

AVP

4.7 (4.2 to 4.8)

4.6 (3.9 to 4.7)^b

4.7 (4.2 to 4.9)^a

4.7 (4.2 to 5.6)^a

Systemic CO₂ production

Control

3.1 (2.7 to 3.5)

3.5 (3.0 to 4.1)^b

4.1 (3.7 to 4.5)^b

4.4 (4.0 to 4.8)^b

(mL/kg/min)

AVP

3.0 (2.7 to 3.4)

3.2 (2.9 to 3.6)

3.4 (3.1 to 3.6)^{a, b}

3.5 (3.2 to 3.8)^{a, b}

Endogenous glucose

Control

2.7 (2.4 to 3.4)

5.6 (4.5 to 6.3)^b

7.2 (5.6 to 8.4)^b

7.7 (7.1 to 10.2)^b

production (mg/kg/min)

AVP

2.5 (2.2 to 2.9)

4.5 (4.0 to 4.8)^b

4.9 (4.7 to 6.8)^b

6.6 (5.0 to 7.5)^b

Systemic glucose

Control

1.9 (1.4 to 2.9)

3.2 (2.1 to 3.4)^b

3.8 (3.1 to 4.3)^b

3.8 (3.4 to 4.5)^b

oxidation (mg/kg/min)

AVP

1.9 (1.6 to 2.4)

2.9 (2.5 to 3.8)^b

3.7 (2.9 to 3.9)^b

3.8 (3.2 to 4.2)^b

Glucose oxidation/production ratio (%)

Control

74 (50 to 104)

54 (51 to 62)^b

52 (50 to 56)

49 (44 to 55)^b

AVP

79 (60 to 93)

64 (57 to 72)^a

62 (57 to 64)^{a, b}

57 (53 to 65)^{a, b}

Arterial lactate

Control

0.9 (0.8 to 1.0)

1.1 (1.0 to 1.3)^b

2.0 (1.3 to 3.6)^b

2.3 (1.8 to 4.1)^b

(mmol/L)

AVP

0.9 (0.8 to 1.0)

0.9 (0.8 to 1.1)

1.2 (1.0 to 1.5)^{a, b}

1.5 (1.3 to 1.9)^{a, b}

Arterial

Control

8 (7 to 9)

12 (11 to 13)

13 (12 to 16)^a

15 (13 to 17)^a

lactate/pyruvate ratio

AVP

9 (8 to 10)

12 (11 to 13)

12 (11 to 13)^a

14 (13 to 15)^a

Arterial pH

Control

7.56 (7.55 to 7.59)

7.50 (7.45 to 7.53)^b

7.47 (7.44 to 7.49)^b

7.44 (7.38 to 7.45)^b

AVP

7.54 (7.49 to 7.57)

7.51 (7.49 to 7.52)^b

7.49 (7.45 to 7.53)^b

7.49 (7.44 to 7.51)^b

Arterial base excess

Control

10.3 (8.8 to 12.3)

9.9 (7.0 to 11.3)

6.0 (3.4 to 8.0)^b

4.1 (-0.2 to 6.2)^b

(mmol/L)

AVP

9.3 (7.9 to 11.0)

9.6 (8.3 to 11.1)

8.9 (6.1 to 9.4)

7.1 (3.9 to 10.7)