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Table 8 PROGRESS DrotAA mortality and clinical outcomes

From: The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomes

Variable DrotAA
n = 882
Non-DrotAA
n = 11,610
Total
n = 12,492
P value
Discharge location by DrotAA use, n (%): (n = 807) (n = 10,537) (n = 11,344) <0.001
   Died 400 (49.6) 5236 (49.7) 5636 (49.7)  
   Community 236 (29.2) 3652 (34.7) 3888 (34.3)  
   Other hospital 73 (9.0) 856 (8.1) 929 (8.2)  
   Extended/Chronic care Institution 83 (10.3) 620 (5.9) 703 (6.2)  
   Other/Unknown 15 (1.9) 173 (1.6) 188 (1.7)  
Hospital mortality for DrotAA therapy, adjusted for Age, 7 OD*, Active Cancer, and Propensity Quartiles Adjusted Odds Ratio 95% Confidence Interval ---- P value
All patients** 0.72 0.603 – 0.86 ---- 0.0003
  1. *Organ Dysfunction (OD).
  2. See METHODS and Additional data file 1 for details and explanation of this covariate
  3. ** Model #9 used for this analysis.
  4. DrotAA = drotrecogin alfa (activated); PROGRESS = Promoting Global Research Excellence in Severe Sepsis.