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Figure 4 | Critical Care

Figure 4

From: Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice

Figure 4

Western blot of left ventricular OTR levels at baseline and day 1 following I/R of the LAD. Left ventricular tissue was dissected and flash frozen for protein extraction both in control (baseline) animals and at day 1 following ischemia/reperfusion (I/R) of the left anterior descending coronary artery (LAD). We chose this timepoint as the enhanced physiologic effect (cardiac suppression) was observed by day 1. In those animals subjected to I/R of the LAD, oxytocin receptor (OTR) expression normalized to β-actin was reduced by 40% compared with controls.

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Critical Care

ISSN: 1364-8535