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Table 2 Ventilatory pattern and respiratory mechanics at enrollment

From: Determinants of weaning success in patients with prolonged mechanical ventilation

 

Successful weaning group

(n = 16)

Failed weaning group

(n = 14)

P value

Ventilatory pattern

   

   VT, mL

336.5 ± 158.3

299.5 ± 213.4

NS

   f, breaths/min

26.1 ± 7.5

32.4 ± 5.2

0.01

   f/VT

109.4 ± 74.5

173.9 ± 103.4

NS

Respiratory mechanics

   

   CLdyn, L/cm H2O

0.049 ± 0.032

0.051 ± 0.035

NS

   RL, cm H2O/L per s

13.4 ± 9.0

12.9 ± 9.4

NS

   PEEPi,dyn, cm H2O

1.93 ± 1.36

2.7 ± 3.1

NS

Inspiratory muscle function

   

   MIP, cm H2O

45.2 ± 19.5

32.7 ± 18.2

NS

   Pdimax, cm H2O

34.9 ± 18.9

25.4 ± 17.3

NS

   Pdisw/Pdimax, percentage

36.1 ± 15.8

54.4 ± 25.5

0.02

   PTPdi/min, cm H2O/s

235.8 ± 126.9

268.0 ± 234.8

NS

   TTdi

0.13 ± 0.065

0.21 ± 0.12

0.02

  1. CLdyn, dynamic lung compliance; f, spontaneous breathing frequency; MIP, maximum inspiratory pressure; NS, not significant; Pdimax, maximum transdiaphragmatic pressure; Pdisw, tidal diaphragmatic pressure; PEEPi,dyn, dynamic intrinsic positive end-expiratory pressure; PTPdi/min, pressure time product of the diaphragm per minute; RL, pulmonary resistance; TTdi, tension-time index of diaphragm; VT, tidal volume.